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原发性膀胱淀粉样变性——3 年后发生上尿路梗阻的患者病例报告。

Primary bladder amyloidosis--case report of a patient with delayed upper urinary tract obstruction 3 years after the diagnosis.

出版信息

Amyloid. 2010 Mar;17(1):36-8. doi: 10.3109/13506121003619377.

Abstract

Primary bladder amyloidosis is a rare disease. There are approximately 100 reported cases. The lesions can be confused with bladder neoplasm and are characterised histologically by the classical apple green birefringence under polarised light. In this article, we report a 51-year-old lady with known history of primary bladder amyloidosis presenting with gross hydronephrosis 3 years after the first diagnosis. Laparoscopic ileal replacement of bilateral ureters was performed. There was no recurrent ureteric obstruction 2 years after surgery. This case demonstrates the progressive nature of primary amyloidosis of bladder. The diagnosis of primary bladder amyloidosis warrants long-term surveillance of upper urinary tract.

摘要

原发性膀胱淀粉样变性是一种罕见疾病。据报道,大约有 100 例病例。病变可能与膀胱肿瘤混淆,组织学上的特征是在偏光下呈现典型的苹果绿双折射。在本文中,我们报告了一位 51 岁的女性,已知患有原发性膀胱淀粉样变性,在首次诊断后 3 年出现严重肾积水。进行了腹腔镜回肠双侧输尿管替代术。手术后 2 年,输尿管无再阻塞。该病例表明原发性膀胱淀粉样变性具有进行性。原发性膀胱淀粉样变性的诊断需要对上尿路进行长期监测。

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