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40岁以上女性中的人乳头瘤病毒:对临床实践的影响及筛查建议

The human papillomavirus in women over 40: implications for practice and recommendations for screening.

作者信息

Montgomery Kymberlee, Bloch Joan Rosen

机构信息

Department of Nursing, Drexel University, Philadelphia, Pennsylvania 19102, USA.

出版信息

J Am Acad Nurse Pract. 2010 Feb;22(2):92-100. doi: 10.1111/j.1745-7599.2009.00477.x.

Abstract

PURPOSE

Cervical cancer is the second leading cause of cancer deaths among women worldwide. Human papillomavirus (HPV) has been shown to be the precursor of cervical cancer in over 99% of these cases. Although preventative measures have greatly reduced the burden of HPV-induced cervical cancer, these measures cannot be utilized by women who are unaware of the existence of HPV and its relationship to their health. Women over the age of 40 are being newly diagnosed with HPV, profoundly impacting their lives and their sense of well-being. This article highlights the necessity for clinicians to assess knowledge, health beliefs, and preventative measures regarding HPV and cervical cancer in women over the age of 40.

DATA SOURCES

Review of scientific literature of knowledge, health beliefs, and preventative measures in women regarding HPV and cervical cancer and clinical practice guidelines.

CONCLUSIONS

Although women aged 40 and above are not specifically considered high risk for HPV infection, many women are testing positive in this age group and are facing the impact of an HPV diagnosis that implicates a sexually transmitted disease and is known to be a precursor to cervical cancer.

IMPLICATIONS FOR PRACTICE

Suggested questions to use for all patients are presented as it is crucial for healthcare providers to understand the healthcare needs of this age group in order to appropriately direct resources and to save the lives of women from this preventable disease.

摘要

目的

宫颈癌是全球女性癌症死亡的第二大主要原因。在超过99%的此类病例中,人乳头瘤病毒(HPV)已被证明是宫颈癌的 precursor。尽管预防措施已大大减轻了HPV引发的宫颈癌负担,但那些未意识到HPV存在及其与自身健康关系的女性无法采用这些措施。40岁以上的女性正被新诊断出感染HPV,这对她们的生活和幸福感产生了深远影响。本文强调临床医生有必要评估40岁以上女性关于HPV和宫颈癌的知识、健康观念及预防措施。

数据来源

对有关女性HPV和宫颈癌的知识、健康观念及预防措施的科学文献以及临床实践指南的综述。

结论

尽管40岁及以上的女性未被特别视为HPV感染的高危人群,但该年龄组中有许多女性检测呈阳性,并且正面临HPV诊断带来的影响,这意味着一种性传播疾病,且已知是宫颈癌的 precursor。

对实践的启示

列出了建议用于所有患者的问题,因为医疗保健提供者了解该年龄组的医疗保健需求对于合理分配资源以及挽救女性免受这种可预防疾病的侵害至关重要。

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