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本文引用的文献

1
Immunoglobulin-free light chains mediate antigen-specific responses of murine dorsal root ganglion neurons.无免疫球蛋白轻链介导小鼠背根神经节神经元的抗原特异性反应。
J Neuroimmunol. 2009 Mar 31;208(1-2):80-6. doi: 10.1016/j.jneuroim.2009.01.008. Epub 2009 Feb 15.
2
IgEb immune complexes activate macrophages through FcgammaRIV binding.IgEb免疫复合物通过FcγRIV结合激活巨噬细胞。
Nat Immunol. 2007 Jul;8(7):762-71. doi: 10.1038/ni1477. Epub 2007 Jun 10.
3
Characterization of myenteric sensory neurons in the mouse small intestine.小鼠小肠肌间感觉神经元的特征分析
J Neurophysiol. 2006 Sep;96(3):998-1010. doi: 10.1152/jn.00204.2006.
4
FcgammaRIV: a novel FcR with distinct IgG subclass specificity.FcγRIV:一种具有独特IgG亚类特异性的新型Fc受体。
Immunity. 2005 Jul;23(1):41-51. doi: 10.1016/j.immuni.2005.05.010.
5
Bone marrow-derived mast cells in mice respond in co-culture to scorpion venom activation of superior cervical ganglion neurites according to level of expression of NK-1 receptors.小鼠骨髓来源的肥大细胞在共培养中,会根据NK-1受体的表达水平,对颈上神经节神经突的蝎毒激活做出反应。
Neurosci Lett. 2004 Dec 6;372(3):185-9. doi: 10.1016/j.neulet.2004.08.008.
6
Expression of Fc epsilon receptor I on primary sensory neurons in mice.小鼠初级感觉神经元上Fcε受体I的表达
Neuroreport. 2004 Sep 15;15(13):2029-31. doi: 10.1097/00001756-200409150-00007.
7
Direct action of immunoglobulin G on primary sensory neurons through Fc gamma receptor I.免疫球蛋白G通过Fcγ受体I对初级感觉神经元的直接作用。
FASEB J. 2004 Jan;18(1):182-4. doi: 10.1096/fj.02-1169fje. Epub 2003 Nov 20.
8
Fc epsilon RI on antigen-presenting cells.抗原呈递细胞上的FcεRI
Curr Opin Immunol. 1996 Dec;8(6):773-7. doi: 10.1016/s0952-7915(96)80003-3.
9
The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals.Fc(ε)RIβ亚基作为Fc(ε)RIγ介导的细胞激活信号的放大器发挥作用。
Cell. 1996 Jun 28;85(7):985-95. doi: 10.1016/s0092-8674(00)81300-8.

功能性 Fc(epsilon 和 gamma)受体的神经元表达证据。

Evidence for neuronal expression of functional Fc (epsilon and gamma) receptors.

出版信息

J Allergy Clin Immunol. 2010 Mar;125(3):757-60. doi: 10.1016/j.jaci.2009.10.054. Epub 2010 Feb 4.

DOI:10.1016/j.jaci.2009.10.054
PMID:20132972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2839037/
Abstract

We report that neurons express functional Fc receptors (including FcεR1), that can be activated by antigen, transmit signals along nerve fibers and . These results open new avenues of investigation in neurogenic inflammation and allergic diseases.

摘要

我们报告称,神经元表达功能性 Fc 受体(包括 FcεR1),这些受体可被抗原激活,沿神经纤维传递信号,这些结果为神经原性炎症和过敏性疾病的研究开辟了新的途径。