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简化活体供肝移植。

Simplifying living donor liver transplantation.

机构信息

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China.

出版信息

Hepatobiliary Pancreat Dis Int. 2010 Feb;9(1):9-14.

Abstract

BACKGROUND

Living donor liver transplantation is a complex surgical operation. Treatment policies and operative techniques evolved in the last two decades.

DATA SOURCES

Our center's experience in living donor liver transplantation was reviewed in conjunction with relevant publications in the literature.

RESULTS

The surgical techniques and perioperative surgical therapeutics could be modified towards simplicity. Examples include regular inclusion of the middle hepatic vein without compromising the venous outflow of the donor's remnant left liver. This provides excellent venous outflow, which is crucial for a small-for-size graft. Immunosuppression and hepatitis B suppression are steroid free and hepatitis B immunoglobulin free respectively.

CONCLUSION

The most practical way to achieve high graft and recipient survival rates with an acceptably low donor risk is through design of a protocol that simplifies the surgery and postoperative management.

摘要

背景

活体供肝肝移植是一项复杂的外科手术。在过去的二十年中,治疗政策和手术技术不断发展。

资料来源

我们中心的活体供肝肝移植经验结合文献中的相关出版物进行了回顾。

结果

手术技术和围手术期治疗可以朝着简化的方向进行修改。例如,经常包括中肝静脉,而不会影响供体剩余左肝的静脉流出。这为小体积移植物提供了极好的静脉流出,这对小体积移植物至关重要。免疫抑制和乙型肝炎抑制分别为无类固醇和无乙型肝炎免疫球蛋白。

结论

通过设计简化手术和术后管理的方案,以可接受的低供者风险实现高移植物和受者存活率的最实际方法是简化手术和术后管理。

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