Department of General Surgery, La Sapienza University of Rome, St. Andrea Hospital, viale Gino Cervi 53 L, 00139, Rome, Italy.
Hepatobiliary Pancreat Dis Int. 2010 Feb;9(1):97-9.
The association between gastric and pancreatic carcinoma is a relatively rare condition. In gastric carcinoma patients, the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics. Gastric cancer associated with pancreatic cancer is uncommon.
We report a case of a 73-year-old patient hospitalized for vomiting and weight loss. Esophagogastroduodenoscopy demonstrated an ulcerative lesion of the gastric antrum. Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3 X 1.7 cm) in the uncinate portion of the pancreas.
The patient underwent pancreaticoduodenectomy according to Whipple regional type I Fortner. Histological examination of the specimen demonstrated a moderately differentiated adenocarcinoma of the stomach and a poorly differentiated ductal adenocarcinoma of the pancreas.
Long survival is rare in patients with associated gastric and pancreatic cancer. Surgical resection remains the only potentially curative treatment.
胃胰癌关联是一种相对罕见的情况。据报道统计，在胃癌患者中，第二肿瘤的患病率为 2.8%至 6.8%。胃癌伴发胰腺癌并不常见。
我们报告了一例 73 岁因呕吐和体重减轻住院的患者。食管胃十二指肠镜检查显示胃窦部有溃疡性病变。计算机断层扫描和磁共振成像显示胃窦和幽门部胃壁增厚，以及在胰腺钩突部有一个结节状肿块（3×1.7 厘米）。
患者根据 Whipple 区域 I Fortner 行胰十二指肠切除术。标本的组织学检查显示胃中分化腺癌和胰腺低分化导管腺癌。
同时患有胃和胰腺癌的患者生存时间通常较短。手术切除仍然是唯一潜在的治愈性治疗方法。
