胃腺癌与胰腺导管腺癌并存。
Synchronous gastric adenocarcinoma and pancreatic ductal adenocarcinoma.
机构信息
Department of General Surgery, La Sapienza University of Rome, St. Andrea Hospital, viale Gino Cervi 53 L, 00139, Rome, Italy.
出版信息
Hepatobiliary Pancreat Dis Int. 2010 Feb;9(1):97-9.
BACKGROUND
The association between gastric and pancreatic carcinoma is a relatively rare condition. In gastric carcinoma patients, the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics. Gastric cancer associated with pancreatic cancer is uncommon.
METHODS
We report a case of a 73-year-old patient hospitalized for vomiting and weight loss. Esophagogastroduodenoscopy demonstrated an ulcerative lesion of the gastric antrum. Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3 X 1.7 cm) in the uncinate portion of the pancreas.
RESULTS
The patient underwent pancreaticoduodenectomy according to Whipple regional type I Fortner. Histological examination of the specimen demonstrated a moderately differentiated adenocarcinoma of the stomach and a poorly differentiated ductal adenocarcinoma of the pancreas.
CONCLUSIONS
Long survival is rare in patients with associated gastric and pancreatic cancer. Surgical resection remains the only potentially curative treatment.
背景
胃胰癌关联是一种相对罕见的情况。据报道统计，在胃癌患者中，第二肿瘤的患病率为 2.8%至 6.8%。胃癌伴发胰腺癌并不常见。
方法
我们报告了一例 73 岁因呕吐和体重减轻住院的患者。食管胃十二指肠镜检查显示胃窦部有溃疡性病变。计算机断层扫描和磁共振成像显示胃窦和幽门部胃壁增厚，以及在胰腺钩突部有一个结节状肿块（3×1.7 厘米）。
结果
患者根据 Whipple 区域 I Fortner 行胰十二指肠切除术。标本的组织学检查显示胃中分化腺癌和胰腺低分化导管腺癌。
结论
同时患有胃和胰腺癌的患者生存时间通常较短。手术切除仍然是唯一潜在的治愈性治疗方法。
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