Kotán Róbert, Pósán János, Sápy Péter, Damjanovich László, Szentkereszty Zsolt
Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Altalános Orvostudományi Kar, Sebészeti Intézet, Debrecen Nagyerdei krt, 98, 4028.
Orv Hetil. 2010 Feb 14;151(7):265-8. doi: 10.1556/OH.2010.28760.
The acute pancreatitis is a relative common disease with incidence of 5-80 per 100000 people of the population. The number of new cases has steadily increased in recent years. The two main etiological factors are alcohol and cholelithiasis. The incidence of alcoholic pancreatitis is higher in male, and the incidence of gallstone pancreatitis is higher in female.
To summarize the difference between the clinical course of biliary and not biliary type of severe acute pancreatitis by analyzing the data of these patients.
139 patients treated with severe acute pancreatitis were divided in two groups: biliary (A group) and non biliary (B group) of origin. The two groups were compared on the basis of sex and age, mortality, morbidity, number of surgery and hospital stay. chi 2 probe was used for the statistical analysis.
The complications in biliary group were more serious. The average mortality rate was 15.1%, 17.8% in group A and 13.8% in group B. The mortality rate of female patients in group A was significantly higher.
Female patients suffering from severe biliary acute pancreatitis have higher morbidity and mortality rate. Therefore an elective cholecystectomy is suggested in old female patients with serious co-morbidity and gallstones, before any complications.
急性胰腺炎是一种相对常见的疾病，发病率为每10万人中有5 - 80例。近年来新发病例数稳步上升。两个主要病因是酒精和胆石症。酒精性胰腺炎的发病率男性较高，而胆石性胰腺炎的发病率女性较高。
通过分析这些患者的数据，总结胆源性和非胆源性重症急性胰腺炎临床病程的差异。
139例接受重症急性胰腺炎治疗的患者分为两组：胆源性（A组）和非胆源性（B组）。对两组患者的性别、年龄、死亡率、发病率、手术次数和住院时间进行比较。采用卡方检验进行统计分析。
胆源性组的并发症更严重。平均死亡率为15.1%，A组为17.8%，B组为13.8%。A组女性患者的死亡率显著更高。
患有重症胆源性急性胰腺炎的女性患者发病率和死亡率更高。因此，建议对患有严重合并症且有胆结石的老年女性患者在出现任何并发症之前择期行胆囊切除术。
