Harper James Garrett, Pilcher Mary Frances, Szlam Sarah, Lind David Scott
Department of General Surgery, Medical College of Georgia, Augusta, GA, USA.
South Med J. 2010 Mar;103(3):256-9. doi: 10.1097/SMJ.0b013e3181c98ba9.
Discoid lupus is an autoimmune disorder with primarily cutaneous manifestations. Carcinomatous changes in discoid lupus can lead to the development of squamous cell carcinoma. While this most often occurs in Caucasians, the presented patient is an African American. She developed numerous squamous cell carcinomas in areas of scarring from discoid lupus. This case illustrates the need for careful observation of discoid lupus for the development of squamous cell carcinoma in the African American patient.
盘状红斑狼疮是一种主要表现为皮肤症状的自身免疫性疾病。盘状红斑狼疮的癌变可导致鳞状细胞癌的发生。虽然这种情况最常发生在白种人中,但该病例患者是一名非裔美国人。她在盘状红斑狼疮的瘢痕部位出现了多处鳞状细胞癌。该病例表明,对于非裔美国患者的盘状红斑狼疮,需要密切观察是否会发展为鳞状细胞癌。