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Gut microbes extend reach to systemic innate immunity.

作者信息

Philpott Dana J, Girardin Stephen E

出版信息

Nat Med. 2010 Feb;16(2):160-1. doi: 10.1038/nm0210-160.

DOI:10.1038/nm0210-160
PMID:20134466
Abstract
摘要

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Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity.Nod1 通过识别微生物群中的肽聚糖增强全身先天免疫。
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本文引用的文献

1
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity.Nod1 通过识别微生物群中的肽聚糖增强全身先天免疫。
Nat Med. 2010 Feb;16(2):228-31. doi: 10.1038/nm.2087. Epub 2010 Jan 17.
2
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing.Nod1信号传导克服了肺炎链球菌对调理吞噬杀伤的抗性。
PLoS Pathog. 2007 Aug 24;3(8):e118. doi: 10.1371/journal.ppat.0030118.
3
Nod-like proteins in immunity, inflammation and disease.免疫、炎症和疾病中的NOD样蛋白。
靶向 GPR120 和其他脂肪酸感知 GPCR 可改善胰岛素抵抗和炎症性疾病。
Trends Pharmacol Sci. 2011 Sep;32(9):543-50. doi: 10.1016/j.tips.2011.04.004. Epub 2011 Jun 12.
4
Shifting the balance: antibiotic effects on host-microbiota mutualism.转变平衡：抗生素对宿主-微生物共生体的影响。
Nat Rev Microbiol. 2011 Apr;9(4):233-43. doi: 10.1038/nrmicro2536. Epub 2011 Feb 28.
5
Phosphorylated dihydroceramides from common human bacteria are recovered in human tissues.常见人体细菌中的磷酸二氢神经酰胺存在于人体组织中。
PLoS One. 2011 Feb 11;6(2):e16771. doi: 10.1371/journal.pone.0016771.
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Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation.孕前肥胖与母体内毒素血症和代谢性炎症有关。
Obesity (Silver Spring). 2011 Mar;19(3):476-82. doi: 10.1038/oby.2010.215. Epub 2010 Oct 7.
Nat Immunol. 2006 Dec;7(12):1250-7. doi: 10.1038/ni1412.
4
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo.Nod1作为一种细胞内受体，可在体内刺激趋化因子的产生并促进中性粒细胞的募集。
J Exp Med. 2006 Jan 23;203(1):203-13. doi: 10.1084/jem.20051229. Epub 2006 Jan 17.
5
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.NOD1在宿主识别含二氨基庚二酸的细菌肽聚糖中起关键作用。
Nat Immunol. 2003 Jul;4(7):702-7. doi: 10.1038/ni945. Epub 2003 Jun 6.
6
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan.Nod1可检测到来自革兰氏阴性菌肽聚糖的一种独特的胞壁肽。
Science. 2003 Jun 6;300(5625):1584-7. doi: 10.1126/science.1084677.
7
Immunoactive peptides, FK-156 and FK-565. III. Enhancement of host defense mechanisms against infection.免疫活性肽FK - 156和FK - 565。III. 增强宿主抗感染防御机制。
J Antibiot (Tokyo). 1983 Aug;36(8):1059-66. doi: 10.7164/antibiotics.36.1059.
8
Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination.肽聚糖作为慢波睡眠的促进剂。II. 一些天然存在的胞壁酰肽的促睡眠和致热活性；与质谱结构测定的相关性。
J Biol Chem. 1984 Oct 25;259(20):12659-62.
9
Peptidoglycans as promoters of slow-wave sleep. I. Structure of the sleep-promoting factor isolated from human urine.
J Biol Chem. 1984 Oct 25;259(20):12652-8.