Department Chemie, Technische Universität Dresden, Bergstrasse 66, 01069 Dresden, Germany.
Org Biomol Chem. 2010 Feb 21;8(4):739-50. doi: 10.1039/b918488k. Epub 2009 Dec 3.
Cholesterol-derived hormones, the dafachronic acids, play a major role in controlling the life cycle and initiating dauer larva formation of the nematode Caenorhabditis elegans. This Perspective describes recent progress in the synthesis of these steroid hormones and their biological function.
胆固醇衍生的激素，即 dafachronic 酸，在控制线虫秀丽隐杆线虫的生命周期和启动 dauer 幼虫形成中起着重要作用。本观点描述了这些类固醇激素的合成及其生物学功能的最新进展。
