Department of Surgery, Flinders University, Flinders Medical Centre, Room 3D211, Bedford Park, SA 5042, Australia.
J Gastrointest Surg. 2010 Apr;14(4):594-600. doi: 10.1007/s11605-010-1158-2. Epub 2010 Feb 5.
Laparoscopic cardiomyotomy is the most common surgical procedure for the treatment of achalasia, although few reports describe long-term surgical outcomes.
The outcomes for 155 patients who underwent a laparoscopic cardiomyotomy with anterior partial fundoplication more than 5 years ago (July 1992 to May 2004) were determined. Patients were followed prospectively at yearly time points using a structured questionnaire which evaluated symptoms of dysphagia, reflux, side-effects, and overall satisfaction with the clinical outcome.
Clinical data were available for 125 patients. Thirteen patients died within 5 years of surgery, four were unable to complete the questionnaire, and one developed esophageal squamous cell carcinoma. Nine patients were lost to follow-up, and three would not answer the questionnaire (92.2% late follow-up). Postoperative dysphagia, odynophagia, chest pain, and heartburn was significantly improved at 1 year, 5 years, and late (5+ years) follow-up, with outcomes stable beyond 12 months. Seventy-seven percent of patients reported a good or excellent result (minimal or no symptoms) at 5 years and 73% at late follow-up. At late follow-up, 90% considered they had made the correct decision to undergo surgery.
At minimum 5 years follow-up, laparoscopic cardiomyotomy for achalasia achieves effective and durable relief of symptoms, and most patients are satisfied with the outcome.
腹腔镜心肌切开术是治疗贲门失弛缓症最常见的手术方法,但很少有报道描述其长期手术效果。
对 155 例 5 年以上(1992 年 7 月至 2004 年 5 月)行腹腔镜心肌切开术加前部分胃底折叠术的患者进行了手术效果评估。通过结构化问卷,每年对患者进行前瞻性随访,评估吞咽困难、反流、副作用等症状,并对临床结局的总体满意度进行评估。
125 例患者的临床资料完整。术后 5 年内 13 例患者死亡,4 例患者无法完成问卷,1 例患者发生食管鳞状细胞癌。9 例患者失访,3 例拒绝回答问卷(92.2%的患者进行了晚期随访)。术后吞咽困难、咽痛、胸痛和烧心在 1 年、5 年和晚期(5 年以上)随访时明显改善,且术后 12 个月后结果稳定。77%的患者在 5 年和晚期随访时报告结果良好或优秀(症状轻微或无)。在晚期随访时,90%的患者认为他们做出了接受手术的正确决定。
在至少 5 年的随访中,腹腔镜心肌切开术治疗贲门失弛缓症可有效且持久地缓解症状,大多数患者对手术结果满意。