Swearingen Alissa, Ghaemmaghami Vafa, Loftus Terrence, Swearingen Christopher J, Salisbury Helen, Gerkin Richard D, Ferrara John
Department of Surgery, Banner Good Samaritan Medical Center, Phoenix, Arizona 85006, USA.
Am Surg. 2010 Jan;76(1):20-4.
This study aims to examine resource utilization and outcomes of trauma patients with extremely high blood alcohol concentrations. We hypothesized that higher blood alcohol concentration (BAC) predicts greater resource utilization and poorer outcomes. A retrospective analysis was performed on trauma patients admitted to an urban Level I trauma center over a 5-year period. Admission BAC categories were constructed using standard laboratory norms and legal definitions. Demographic data, premorbid conditions, injury severity scores (ISS), resource utilization (intensive care unit (ICU) admission rates/length of stay, total hospital days, use of consultants), and mortality were analyzed. Positive BAC on admission was associated with increased ISS (P < 0.001), length of stay (P < 0.003), and total ICU days (P < 0.001). Increased BAC admission level of patients was associated with a decreased ISS score (P = 0.0073), a higher probability of ICU admission (P = 0.0013), and an increased percentage of ICU days (P = 0.001). A positive BAC at admission was a significant predictor of both ICU admission and mortality (odds ratios 1.72 and 1.27, respectively). This study demonstrates that a positive BAC is associated with increased ISS, increased resource utilization, and worsened outcomes. Extreme levels of BAC are associated with increased resource utilization despite lower injury severity scores.
本研究旨在探讨血液酒精浓度极高的创伤患者的资源利用情况及预后。我们假设较高的血液酒精浓度(BAC)预示着更高的资源利用率和更差的预后。对一家城市一级创伤中心5年内收治的创伤患者进行了回顾性分析。根据标准实验室标准和法律定义构建入院BAC类别。分析了人口统计学数据、病前状况、损伤严重程度评分(ISS)、资源利用情况(重症监护病房(ICU)入住率/住院时间、总住院天数、会诊使用情况)和死亡率。入院时BAC呈阳性与ISS增加(P < 0.001)、住院时间延长(P < 0.003)和ICU总天数增加(P < 0.001)相关。患者入院时BAC水平升高与ISS评分降低(P = 0.0073)、ICU入院概率增加(P = 0.0013)和ICU天数百分比增加(P = 0.001)相关。入院时BAC呈阳性是ICU入院和死亡率的显著预测因素(优势比分别为1.72和1.27)。本研究表明,入院时BAC呈阳性与ISS增加、资源利用增加和预后恶化相关。尽管损伤严重程度评分较低,但极高水平的BAC与资源利用增加相关。