Department of Dermatology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Dermatol Ther. 2010 Jan-Feb;23(1):72-81. doi: 10.1111/j.1529-8019.2009.01292.x.
The ultraviolet (UV) light spectrum has long been known to induce biologic effect on the skin. For a large number of cutaneous disorders, phototherapy and photochemotherapy are effective therapeutic options with excellent safety profiles and well-documented side effects. Despite their ease of administration and benefits, phototherapeutic treatment modalities require appropriate space for the equipment, trained staff, and patient education prior to initiating treatment. However, when the initial barriers to treatment can be overcome, UV therapy can offer patients significant relief from their cutaneous disease. Furthermore, UVB-based phototherapy can produce significant alteration to vitamin D levels. With the recent research implicating association of low vitamin D levels with a variety of health conditions, whether patients receiving phototherapy or, more specifically, those getting vitamin D supplement may be protected from these diseases remains to be established.
紫外线（UV）光谱早已被证实对皮肤具有生物学效应。对于许多皮肤疾病，光疗和光化学疗法是有效的治疗选择，具有出色的安全性和记录良好的副作用。尽管这些治疗方法易于管理且有益，但光疗治疗方式需要为设备、训练有素的工作人员和患者在开始治疗前提供适当的空间和教育。然而，一旦克服了初始治疗障碍，紫外线治疗就能为患者的皮肤疾病带来显著缓解。此外，基于 UVB 的光疗可以显著改变维生素 D 水平。最近的研究表明，维生素 D 水平低与多种健康状况有关，因此，接受光疗的患者，或者更具体地说，接受维生素 D 补充的患者是否可以预防这些疾病，仍有待确定。
