Department of Dermatology, Henry Ford Hospital, Detroit, MI 48202, USA.
Mayo Clin Proc. 2012 Apr;87(4):372-80. doi: 10.1016/j.mayocp.2011.12.010. Epub 2012 Mar 14.
Vitamin D is a fat-soluble steroid hormone that is crucial for human health and has recently generated controversy regarding its role in human health and disease. In this Special Article, we discuss our dermatologic perspective on vitamin D in a question-and-answer format. We discuss methods of obtaining vitamin D, including cutaneous photobiosynthesis, diet, and supplements and include the recent US Institute of Medicine recommendations. Other reviewed topics include the associations among skin pigmentation, climate, photoprotection, and vitamin D levels. We also elaborate on the popular interest in sun exposure as a method of normalizing vitamin D levels in the context of the risks of solar and artificial radiation. We also discuss groups at risk for vitamin D inadequacy, the need for testing serum vitamin D levels, and the role of phototherapy in patients with malabsorption conditions and hypervitaminosis D, with a focus on patients with sarcoidosis. Finally, we summarize our recommendations on vitamin D.
维生素 D 是一种脂溶性类固醇激素，对人类健康至关重要，最近其在人类健康和疾病中的作用引起了争议。在这篇专题文章中，我们以问答的形式讨论了我们皮肤科医生对维生素 D 的看法。我们讨论了获得维生素 D 的方法，包括皮肤光生物合成、饮食和补充剂，并包括美国医学研究所的最新建议。其他审查的主题包括皮肤色素沉着、气候、光保护和维生素 D 水平之间的关联。我们还详细阐述了在太阳和人工辐射风险的背景下，人们对阳光暴露作为一种使维生素 D 水平正常化的方法的浓厚兴趣。我们还讨论了维生素 D 不足的风险群体、检测血清维生素 D 水平的必要性，以及光疗在吸收不良和维生素 D 中毒患者中的作用，重点是类肉瘤病患者。最后，我们总结了我们对维生素 D 的建议。
