Li Qing-song, Zhang Xing-ru, Zou Hai-dong, Peng Jin-juan, Shi Cai-cai, Zhou Huan-ming, Zhang Gui-li, Xiang Min-hong, Li Yi-jie
Department of Ophthalmology, Putuo Hospital Affiliated to Shanghai University of Traditional Medicine, Shanghai 200062, China.
Zhonghua Yan Ke Za Zhi. 2009 Sep;45(9):793-8.
To investigate the prevalence and relative factors of conjunctivochalasis among people over 60 years old in Caoyangxincun community of Shanghai.
A cross-sectional study based on local residents in this community was carried out from September 2008 to October 2008. Cluster sampling was used in randomly selecting individuals aged > or = 60 years. Slit-lamp ophthalmoscope was used for eye examination and diagnosis. The survey was preceded by a pilot study where operational methods were refined and quality assurance evaluation was carried out. A database was set using SPSS 10.0 software, Chi-square test was used for data analysis.
2110 residents took part in this study, with the response rate 94.85%. 930 cases (1762 eyes) were confirmed as conjunctivochalasis, so the prevalence rate is 44.08%. The prevalence of conjunctivochalasis was increasing with age (chi(2) = 10.44, P < 0.01). 556 cases (943 eyes) were confirmed as degree I, 246 cases (647 eyes) as degree II, 120 cases (162 eyes) as degree III and the rest 8 cases (10 eyes) as degree IV. Several symptoms, such as blurred vision, asthenopia and eye pain were more frequent in patient group than in the normal ones (chi(2) value was 15.44, 20.54 and 19.74, respectively, P < 0.01). In the disease eyes, the conjunctiva usually piled up on the nasal and temporal side (944 eyes, 53.58%), the location of inferior lid margin was usually above corneal limbus (2589 eyes, 61.35%) and inferior lid margin entropion and introversion were always found (7.04% and 6.63%). Abnormal lacrimal river was found in 87.23% of the diseased eyes, more than the non-conjunctivochalasis eyes (chi(2) = 1615.81, P < 0.01).
Conjunctivochalasis is a common eye disease in aged population, with obvious signs and symptoms of ocular surface and lacrimal river impairment. In the local residents, most patients were classified as minimal or moderate degree. The location of inferior lid margin and the tension of inferior lid may be related factor of conjunctivochalasis.
调查上海曹杨新村社区60岁以上人群结膜松弛症的患病率及其相关因素。
于2008年9月至10月对该社区居民进行横断面研究。采用整群抽样方法随机选取年龄≥60岁的个体。使用裂隙灯显微镜进行眼部检查和诊断。在调查前进行了预试验，对操作方法进行了完善并开展了质量保证评估。使用SPSS 10.0软件建立数据库，采用卡方检验进行数据分析。
2110名居民参与了本研究，应答率为94.85%。确诊结膜松弛症930例（1762只眼），患病率为44.08%。结膜松弛症的患病率随年龄增长而升高（χ² = 10.44，P < 0.01）。确诊为Ⅰ度556例（943只眼），Ⅱ度246例（647只眼），Ⅲ度120例（162只眼），Ⅳ度8例（10只眼）。视物模糊、眼疲劳和眼痛等症状在患者组中比正常组更常见（χ²值分别为15.44、20.54和19.74，P < 0.01）。患眼中，结膜通常在鼻侧和颞侧堆积（944只眼，53.58%），下睑缘位置通常在角膜缘上方（2589只眼，61.35%），且常伴有下睑缘内翻和内卷（分别为7.04%和6.63%）。87.23%的患眼中发现泪河异常，高于非结膜松弛症眼（χ² = 1615.81，P < 0.01）。
结膜松弛症是老年人群中的常见眼病，有明显的眼表和泪河损害体征及症状。在当地居民中，大多数患者为轻度或中度。下睑缘位置及下睑张力可能是结膜松弛症的相关因素。
