Department of Ophthalmology, Shanghai First People's Hospital, Affiliated Shanghai Jiaotong University, Shanghai 200080, China.
BMC Public Health. 2011 Mar 31;11:198. doi: 10.1186/1471-2458-11-198.
In a previous hospital-based study, conjunctivochalasis was diagnosed in 85.24% of 1416 patients aged 1 to 94 years and in 98.5% of patients aged 60 or older. This report is the first to present data from a large scale epidemiologic study on conjunctivochalasis in a community-based population, thereby helping to better identify the severity of conjunctivochalasis in the general population.
This community-based epidemiologic study was conducted to evaluate prevalence rates and related factors of conjunctivochalasis among people over 60 years old in the CaoYangXinCun community, Shanghai, China. Cluster sampling was used in randomly selected local residents aged no less than 60 years. A cross-sectional study using a slit-lamp ophthalmoscope for examination was carried out from September 2008 to October 2008. A modified grading system based on the well-accepted Meller and Tseng's system was used. SPSS10.0 software was used for data and statistical analysis.
A total of 2110 residents took part in this study, with a response rate of 94.85%. Among these, 930 cases were confirmed as conjunctivochalasis, with a prevalence rate of 44.08%. The prevalence rate increased with age (X2 = 10.44, P < 0.01). A total of 1762 eyes were confirmed as conjunctivochalasis eyes. Of these eyes, 943 were classified as Grade I (53.52%), 647 as Grade II (36.72%), 162 as Grade III (9.19%), and the remaining 10 eyes as Grade IV (0.57%). The conjunctiva usually accumulated on the nasal and temporal areas of the conjunctival sac (944 eyes, 53.58%).
Although the rate estimated in the present study is not as high as reported in the former hospital-based study, conjunctivochalasis is considered a common age-related eye disease, deserving more attention to its early diagnosis.
在之前的一项基于医院的研究中，1416 名 1 至 94 岁的患者中有 85.24%被诊断为结膜松弛症，而 60 岁或以上的患者中 98.5%被诊断为结膜松弛症。本报告首次提供了一项基于社区人群的结膜松弛症大型流行病学研究的数据，从而有助于更好地识别普通人群中结膜松弛症的严重程度。
本项基于社区的流行病学研究旨在评估中国上海曹杨新村社区 60 岁以上人群中结膜松弛症的患病率及相关因素。采用整群抽样方法随机选取当地年龄不低于 60 岁的居民。2008 年 9 月至 10 月间采用裂隙灯显微镜进行横断面研究。采用改良的分级系统，该系统基于公认的 Meller 和 Tseng 系统。采用 SPSS10.0 软件进行数据和统计学分析。
共有 2110 名居民参加了这项研究，应答率为 94.85%。其中，930 例被确诊为结膜松弛症，患病率为 44.08%。患病率随年龄增长而增加（X2 = 10.44，P < 0.01）。共有 1762 只眼被确诊为结膜松弛症眼。这些眼中，943 只眼为Ⅰ级（53.52%），647 只眼为Ⅱ级（36.72%），162 只眼为Ⅲ级（9.19%），其余 10 只眼为Ⅳ级（0.57%）。结膜通常堆积在结膜囊的鼻侧和颞侧（944 只眼，53.58%）。
尽管本研究估计的患病率不如之前的基于医院的研究高，但结膜松弛症被认为是一种常见的与年龄相关的眼病，值得更多关注其早期诊断。
