Ophthalmology Department, Faculty of Medicine, Yozgat Bozok University, Adnan Menderes Bulvarı, Yozgat, Turkey.
Int Ophthalmol. 2024 Feb 9;44(1):39. doi: 10.1007/s10792-024-02936-x.
To evaluate the correlation between clinical tests, patient symptoms, and conjunctivochalasis in contact lens wearers and non-wearers.
This study comprised 40 eyes of 40 current soft contact lens users and 40 eyes of 40 control subjects. Cross-sectional areas of conjunctivochalasis at three locations (nasal, central, temporal) during straight and downward gazes were determined using anterior segment optical coherence tomography in all participants. Tear film break up time test and Schirmer test with anesthesia were performed and for evaluation of symptoms, the participants completed ocular surface disease index questionnaire.
During straight gaze, the mean cross-sectional areas of conjunctivochalasis were 0.0112 ± 0.009 and 0.006 ± 0.005 mm at nasal, 0.0096 ± 0.007 and 0.002 ± 0.004 mm at central, 0.0176 ± 0.014 and 0.008 ± 0.009 mm at temporal in contact lens and control groups, respectively. Regardless of location and gaze direction, the mean cross-sectional conjunctivachalasis areas of the contact lens group were significantly higher than those of the controls (all, p < 0.05). Significant positive correlations between ocular surface disease index score and measured conjunctivachalasis areas (in all sites) during straight gaze and downward gaze were observed in the contact lens group (all, p < 0.05 and r > 0.450).
Wearing soft contact lenses is associated with increased conjunctivochalasis areas. Anterior segment optical coherence tomography determined conjunctivochalasis area is an objective clinical measurement value that is positively correlated with patients' symptoms in soft contact lens wearers.
评估接触镜佩戴者和非佩戴者的临床检查、患者症状与结膜松弛症之间的相关性。
本研究纳入 40 名软性隐形眼镜当前使用者的 40 只眼和 40 名对照者的 40 只眼。所有参与者均接受眼前节光学相干断层扫描，以确定直眼和下视时三个部位（鼻侧、中央、颞侧）的结膜松弛症横截面积。进行泪膜破裂时间试验和麻醉下的 Schirmer 试验，并通过眼表疾病指数问卷评估症状。
直眼时，接触镜组鼻侧、中央和颞侧的结膜松弛症平均横截面积分别为 0.0112±0.009 和 0.006±0.005、0.0096±0.007 和 0.002±0.004、0.0176±0.014 和 0.008±0.009mm，对照组分别为 0.002±0.004、0.003±0.003、0.005±0.003 和 0.001±0.002mm。无论位置和注视方向如何，接触镜组的平均横截面积均显著高于对照组（均，p<0.05）。接触镜组直眼和下视时下，眼表疾病指数评分与测量的结膜松弛症横截面积（所有部位）呈显著正相关（均，p<0.05，r>0.450）。
软性隐形眼镜的佩戴与结膜松弛症横截面积的增加有关。眼前节光学相干断层扫描确定的结膜松弛症横截面积是软性隐形眼镜佩戴者与患者症状呈正相关的客观临床测量值。
Zotero 插件