Department of Occupational Medicine, Kaiser Permanente Southern California, Los Angeles, CA, USA.
Dermatitis. 2010 Jan-Feb;21(1):E5-6.
Thioureas are used as additives in rubber products and as antidegradants for natural rubber latex. They are an uncommon cause of allergic contact dermatitis. This case represents an example of occupational allergic contact dermatitis solely from thioureas in rubber products and no cross-reactivity with other rubber allergens. Standard patch tests may fail to detect thiourea-induced allergic contact dermatitis, so clinicians should consider thiourea sensitization in rubber allergy.
硫脲类化合物被用作橡胶制品的添加剂和天然胶乳的抗降解剂。它们是一种不常见的过敏性接触性皮炎病因。本病例代表了仅由橡胶制品中的硫脲类化合物引起的职业性过敏性接触性皮炎，与其他橡胶变应原无交叉反应。标准斑贴试验可能无法检测出硫脲类引起的过敏性接触性皮炎，因此临床医生应考虑橡胶过敏中的硫脲类致敏。
