Respiratory Medicine Research Programme, Centre for Infection and Immunity, Queen's University, Belfast BT12 6BN, UK.
QJM. 2010 Apr;103(4):243-51. doi: 10.1093/qjmed/hcp194. Epub 2010 Feb 4.
Delirium is an acute organ dysfunction common amongst patients treated in intensive care units. The associated morbidity and mortality are known to be substantial. Previous surveys have described which screening tools are used to diagnose delirium and which medications are used to treat delirium, but these data are not available for the United Kingdom.
This survey aimed to describe the UK management of delirium by consultant intensivists. Additionally, knowledge and attitudes towards management of delirium were sought. The results will inform future research in this area.
A national postal survey of members of the UK Intensive Care Society was performed. A concise two page questionnaire survey was sent, with a second round of surveys sent to non-respondents after 6 weeks. The questionnaire was in tick-box format.
Six hundred and eighty-one replies were received from 1308 questionnaires sent, giving a response rate of 52%. Twenty-five percent of respondents routinely screen for delirium, but of these only 55% use a screening tool validated for use in intensive care. The majority (80%) of those using a validated instrument used the Confusion Assessment Method for the Intensive Care Unit. Hyperactive delirium is treated pharmacologically by 95%; hypoactive delirium is treated pharmacologically by 25%, with haloperidol the most common agent used in both. Over 80% of respondents agreed that delirium prolongs mechanical ventilation and hospital stay and requires active treatment.
This UK survey demonstrates screening for delirium is sporadic. Pharmacological treatment is usually with haloperidol in spite of the limited evidence to support this practice. Hypoactive delirium is infrequently treated pharmacologically.
谵妄是重症监护病房患者常见的急性器官功能障碍。其相关发病率和死亡率是众所周知的。先前的调查已经描述了哪些筛查工具用于诊断谵妄,哪些药物用于治疗谵妄,但这些数据不适用于英国。
本调查旨在描述英国顾问重症监护医生对谵妄的管理。此外,还寻求了他们对谵妄管理的知识和态度。调查结果将为该领域的未来研究提供信息。
对英国重症监护学会的成员进行了全国性的邮寄调查。发送了一份简洁的两页问卷调查,6 周后对未回复者进行了第二轮调查。问卷采用勾选格式。
从 1308 份问卷中收到了 681 份回复,回复率为 52%。25%的受访者常规筛查谵妄,但其中只有 55%使用了经证实可用于重症监护的筛查工具。大多数(80%)使用经过验证的工具的人使用了重症监护病房的意识模糊评估方法。95%的人使用药物治疗活跃性谵妄,25%的人使用药物治疗活动性谵妄,两者最常用的药物均为氟哌啶醇。超过 80%的受访者同意谵妄会延长机械通气和住院时间,需要积极治疗。
这项英国调查表明,对谵妄的筛查是零星的。尽管有有限的证据支持这种做法,但药物治疗通常使用氟哌啶醇。很少有药物治疗活性低的谵妄。