Martorell Reynaldo, Nguyen Phuong
Hubert Department of Global Health and Nutrition and Health Sciences Program, Emory University, Atlanta, GA, USA.
Nestle Nutr Workshop Ser Pediatr Program. 2010;65:99-118; discussion 118-21. doi: 10.1159/000281151. Epub 2010 Feb 1.
Early childhood growth failure is a significant public health problem in developing countries. We examine relationships between low birthweight and stunting with child development. Compared to children born with normal birthweight, low birth-weight children have substantially poorer cognitive and schooling outcomes later in life. Linear growth failure leading to stunting mostly occurs before age 2 years, with stunting in older children reflecting growth failure in early life. Many studies show that stunting is associated with poor mental and motor development in infants and with low scores in cognitive tests, increased frequency of behavioral problems and poor school achievement in older children. Very few studies have assessed the relative importance for development of prenatal vs. postnatal growth failure and even fewer have done so using appropriate statistical techniques. The limited evidence to date suggests growth during the first 2 years of life is more important than growth at any other time, including the prenatal period, for predicting later cognitive development, schooling and educational achievement. In conclusion, children in settings of poverty who experience growth failure prior to age 2 years have reduced potential to succeed in school and to be productive members of society.
幼儿期生长发育迟缓是发展中国家一个重大的公共卫生问题。我们研究了低出生体重和发育迟缓与儿童发育之间的关系。与出生体重正常的儿童相比,低出生体重儿童在日后的生活中认知和学业成绩明显更差。导致发育迟缓的线性生长发育迟缓大多发生在2岁之前,大龄儿童的发育迟缓反映了早期生活中的生长发育迟缓。许多研究表明,发育迟缓与婴儿的心理和运动发育不良、认知测试得分低、行为问题频发以及大龄儿童学业成绩差有关。很少有研究评估产前与产后生长发育迟缓对发育的相对重要性,使用适当统计技术进行此类评估的研究更少。迄今为止有限的证据表明,对于预测日后的认知发展、学业和教育成就而言,生命最初2年的生长比包括孕期在内的其他任何时期的生长都更为重要。总之,2岁之前经历生长发育迟缓的贫困儿童在学业上取得成功并成为社会有生产力成员的潜力降低。