Han Ying, Liu Hong-wei
Department of TCM and Oral Medicine, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2010 Feb 18;42(1):117-21.
A large number of studies showed that hairy leukoplakia, pseudomembranous candidiasis, Kaposi' sarcoma, non-Hodgkin's lymphoma, linear gingival erythema, necrotizing ulcerative periodontitis and necrotizing ulcerative gingivitis were the most common lesions in patients with HIV infection and AIDS, and their higher prevalence and incidence rates correlated with the falling CD4 counts and higher virus load of the patients. The use of highly active antiretroviral therapy (HAART) was associated with decreases in the prevalence of oral diseases. Oral manifestations may represent early signs of AIDS disease and call attention to disease progression. Oral fluid has been shown to possess superior sensitivity for HIV antibody detection as serum.
大量研究表明，毛状白斑、假膜性念珠菌病、卡波西肉瘤、非霍奇金淋巴瘤、线性牙龈红斑、坏死性溃疡性牙周炎和坏死性溃疡性牙龈炎是HIV感染和艾滋病患者最常见的病变，其较高的患病率和发病率与患者CD4细胞计数下降及病毒载量升高相关。使用高效抗逆转录病毒疗法（HAART）与口腔疾病患病率降低有关。口腔表现可能是艾滋病疾病的早期迹象，并提醒注意疾病进展。已证明口腔液对HIV抗体检测的敏感性优于血清。
