Department of Plant Systems Biology; Flanders Institute for Biotechnology (VIB) and Department of Molecular Genetics; Ghent University; Gent Belgium.
Plant Signal Behav. 2008 Oct;3(10):846-7. doi: 10.4161/psb.3.10.5993.
Jasmonates (JAs) control many aspects of plant defense and development, for instance by inhibiting growth and eliciting secondary metabolism. The mechanisms by which JAs regulate these processes are currently under intensive investigation. Examination of transcriptional changes upon methyl jasmonate (MeJA) perception in a fast-growing Arabidopsis thaliana cell suspension culture revealed a quick and direct dual effect of JAs on the plant's cellular processes. Simultaneously, JA-elicited Arabidopsis cells activated phenylpropanoid metabolism and repressed cell cycle progression. Early JA response genes were predominantly implicated in transcriptional regulation and JA biosynthesis. In two parallel screens, we identified both early responsive transcriptional activators (ORA47 and MYC2) and transcriptional repressors (STZ/ZAT10 and AZF2) that putatively regulate the expression of the JA biosynthesis gene LOX3. In this addendum, we provide additional data demonstrating that MYC2, STZ/ZAT10 and AZF2 might also control the expression of JAZ1/TIFY10a that encodes a key repressor in the JA signaling cascade.
茉莉酸（JAs）控制着植物防御和发育的许多方面，例如抑制生长和引发次生代谢。目前正在深入研究 JAs 调节这些过程的机制。在快速生长的拟南芥悬浮细胞培养物中，研究茉莉酸甲酯（MeJA）感知时的转录变化，揭示了 JAs 对植物细胞过程的快速直接的双重影响。同时，JA 诱导的拟南芥细胞激活苯丙烷代谢并抑制细胞周期进程。早期的 JA 反应基因主要参与转录调控和 JA 生物合成。在两个平行的筛选中，我们鉴定了早期响应的转录激活因子（ORA47 和 MYC2）和转录抑制因子（STZ/ZAT10 和 AZF2），它们可能调节 LOX3 基因的 JA 生物合成。在本附录中，我们提供了额外的数据，证明 MYC2、STZ/ZAT10 和 AZF2 也可能控制 JAZ1/TIFY10a 的表达，JAZ1/TIFY10a 编码 JA 信号级联中的关键抑制因子。
