人类致癌物硫芥对沙门氏菌和小鼠骨髓的遗传活性。
Genetic activity of the human carcinogen sulphur mustard towards Salmonella and the mouse bone marrow.
作者信息
Ashby J, Tinwell H, Callander R D, Clare N
机构信息
ICI Central Toxicology Laboratory, Macclesfield, Ches., Great Britain.
出版信息
Mutat Res. 1991 May;257(3):307-11. doi: 10.1016/0165-1110(91)90004-f.
PMID:2014034
Abstract
Sulphur mustard is clearly mutagenic to the repair-proficient (uvrB+) strain G46 of S. typhimurium. It is also a micronucleus-inducing agent to the mouse bone marrow. These data strengthen the database indicating that most human carcinogens are genotoxic.
摘要
硫芥对鼠伤寒沙门氏菌修复功能正常（uvrB+）的菌株G46具有明显的致突变性。它对小鼠骨髓也是一种微核诱导剂。这些数据强化了表明大多数人类致癌物具有基因毒性的数据库。
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