Key Laboratory of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, PR China.
Nat Prod Res. 2010 Feb;24(3):294-9. doi: 10.1080/14786410903034330.
A new glycoside compound (1) was isolated from the starfish Asteria amurensis Lutken. The structure for compound 1 was identified as 1-O-{beta-D-quinovopyranosyl-(1-2)-beta-D-fucopyranosyl-(1-4)-[beta-D-fucopyranosyl(1-2)] beta-D-quinovopyranosyl}-butanol by extensive NMR experiments as well as chemical evidence. The effects of compound 1 on UMR106 cell proliferation were screened by MTT assay. The results indicate that compound 1 (0.01-100 microM) significantly promotes osteoblastic proliferation.
从星状星盘 Asteria amurensis Lutken 中分离得到一种新的糖苷化合物（1）。通过广泛的 NMR 实验以及化学证据，确定化合物 1 的结构为 1-O-{β-D-奎诺吡喃糖基-(1-2)-β-D-岩藻吡喃糖基-(1-4)-[β-D-岩藻吡喃糖基(1-2)]β-D-奎诺吡喃糖基}-丁醇。通过 MTT assay 筛选化合物 1 对 UMR106 细胞增殖的影响。结果表明，化合物 1（0.01-100 μM）显著促进成骨细胞增殖。
