银屑病患者的牙周炎：一项盲法、病例对照研究。
Periodontitis in psoriasis patients: a blinded, case-controlled study.
机构信息
Department of Periodontology, Institute of Clinical Odontology, University of Oslo, Oslo, Norway.
出版信息
Acta Odontol Scand. 2010 May;68(3):165-70. doi: 10.3109/00016350903583678. Epub 2010 Feb 8.
OBJECTIVE
Destructive periodontitis is one of the most frequent and widespread bacterial infections in humans. Psoriasis is a common condition in the general population. Since both psoriasis and periodontal diseases are characterized by an exaggerated response of the immune system to the epithelial surface microbiota, there may possibly be an association between these two conditions. The aim of the present pilot study was to investigate the prevalence of periodontal disease in psoriasis patients compared to healthy controls.
MATERIAL AND METHODS
Dental bite-wing X-rays were obtained from 155 psoriasis patients aged 45-60 years, as well as from 155 age- and gender-matched controls. All X-rays were examined by the same investigator for accumulated destructive periodontitis using bone level and loss of teeth as endpoints.
RESULTS
A significantly lower radiographic bone level (p < 0.001) and a significantly higher number of missing teeth (p < 0.001) were observed in the psoriasis cases compared to the controls.
CONCLUSION
Our study indicates that psoriasis patients experience more bone loss than age- and gender-matched controls.
目的
破坏性牙周炎是人类最常见和广泛的细菌感染之一。银屑病是一种常见的疾病。由于银屑病和牙周病的特征都是免疫系统对上皮表面微生物群的过度反应，因此这两种情况之间可能存在关联。本初步研究的目的是调查与健康对照组相比，银屑病患者牙周病的患病率。
材料和方法
从 155 名年龄在 45-60 岁的银屑病患者和 155 名年龄和性别匹配的对照组中获得了牙科咬翼 X 光片。所有 X 光片均由同一位研究者使用骨水平和牙齿缺失作为终点来检查累积破坏性牙周炎。
结果
与对照组相比，银屑病患者的影像学骨水平显著降低（p<0.001），牙齿缺失数量显著增加（p<0.001）。
结论
我们的研究表明，与年龄和性别匹配的对照组相比，银屑病患者经历了更多的骨质流失。
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