Department of Dental Clinics, Oral Pathology, and Oral Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Pontific Catholic University of Minas Gerais, Belo Horizonte, Minas Gerais, 31270-901, Brazil.
Clin Oral Investig. 2021 May;25(5):2827-2836. doi: 10.1007/s00784-020-03600-1. Epub 2020 Sep 21.
To evaluate the periodontal condition and the impact of oral health on the quality of life (OHRQL) among individuals with and without psoriasis.
This case-control study comprised 295 individuals with psoriasis and 359 controls. A full mouth examination was performed for all periodontal clinical parameters. To evaluate OHRQL, the Oral Impact on Daily Performance (OIDP) questionnaire was applied. Data was analyzed using the chi-square, Fischer, Kruskal-Wallis, Mann-Whitney, and Bootstrap intervals tests to determine different profiles in relation to the OIDP.
Individuals with psoriasis had a 1.40 greater chance of having periodontitis than controls (OR = 1.40 95%CI: 1.01-1.93; p = 0.019). Individuals with psoriasis with periodontitis (+P) had greater impacts on OHRQL (13.76 ± 15.58), when compared with those without periodontitis (-P) (4.83 ± 8.25; p < 0.001). Additionally, psoriasis +P stage III/IV patients (13.94 ± 15.68) had worse indicators than controls -P (9.49 ± 22.54; p = 0.001). The final multivariate model demonstrated higher OIDP scores related to the following variables: diabetes, anxiolytics use, periodontitis, and psoriasis, showing worse OHRQoL.
This study demonstrated an important risk association between psoriasis and periodontitis, as both diseases demonstrated worse OHRQL indicators. Moreover, the severity of periodontitis and psoriasis significantly increased these negative impacts.
Practical implications: Multidisciplinary interaction is desirable to improve the impact of these diseases on the QoL of individuals with psoriasis and periodontitis.
评估银屑病患者和非银屑病患者的牙周状况和口腔健康对生活质量（OHRQL）的影响。
本病例对照研究纳入了 295 名银屑病患者和 359 名对照。对所有牙周临床参数进行了全面口腔检查。为了评估 OHRQL，应用了口腔日常活动影响问卷（OIDP）。使用卡方、Fisher、Kruskal-Wallis、Mann-Whitney 和 Bootstrap 区间检验分析数据，以确定与 OIDP 相关的不同特征。
银屑病患者发生牙周炎的几率比对照组高 1.40 倍（OR = 1.40 95%CI：1.01-1.93；p = 0.019）。与无牙周炎（-P）的银屑病患者相比（4.83 ± 8.25；p < 0.001），有牙周炎（+P）的银屑病患者对 OHRQL 的影响更大（13.76 ± 15.58）。此外，银屑病+P Ⅲ/Ⅳ期患者（13.94 ± 15.68）的指标比对照组 -P 更差（9.49 ± 22.54；p = 0.001）。最终的多变量模型表明，与糖尿病、抗焦虑药使用、牙周炎和银屑病相关的 OIDP 评分更高，表明 OHRQoL 更差。
本研究表明银屑病和牙周炎之间存在重要的风险关联，这两种疾病都表现出更差的 OHRQL 指标。此外，牙周炎和银屑病的严重程度显著增加了这些负面影响。
实际意义：需要多学科的互动，以改善银屑病和牙周炎患者这些疾病对生活质量的影响。
