The Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Am J Drug Alcohol Abuse. 2010 Jan;36(1):46-51. doi: 10.3109/00952990903544844.
Bupropion's efficacy for smoking cessation in pregnant women is unknown.
To determine if substance-dependent women prescribed bupropion smoked fewer cigarettes/day than those prescribed citalopram/escitalopram or no antidepressant medication.
Comparison of smoking in bupropion (n = 11), citalopram/escitalopram (n = 17), and no antidepressant (n = 28) groups.
Trend for greater decrease in smoking for the bupropion vs. citalopram/escitalopram group [-6.4 vs. -.4 cigarettes/day (p = .276)], although the bupropion decrease was similar to that seen in the no antidepressant group [-5.3 cigarettes/day].
Data support continued study of bupropion in depressed pregnant substance-dependent smokers.
安非他酮对于孕妇戒烟的疗效尚不明确。
确定与服用西酞普兰/艾司西酞普兰或未服用抗抑郁药物相比,服用安非他酮的物质依赖女性每天吸烟的数量是否更少。
比较安非他酮组(n = 11)、西酞普兰/艾司西酞普兰组(n = 17)和未用抗抑郁药组(n = 28)的吸烟情况。
安非他酮组比西酞普兰/艾司西酞普兰组的吸烟量下降趋势更大[-6.4 比 -.4 支/天(p =.276)],尽管安非他酮的下降幅度与未用抗抑郁药组相似[-5.3 支/天]。
数据支持在患有抑郁症的物质依赖吸烟孕妇中继续研究安非他酮。