Unité de Soins et de Cardiologie Interventionnelle, Nouvelles Cliniques Nantaises, Nantes, France.
EuroIntervention. 2010 Feb;5(7):814-20. doi: 10.4244/eijv5i7a136.
Isolated, high-grade coronary bifurcation lesions located at the side branch (SB) ostium (Medina type 0,0,1) are uncommon and their specific treatment has not been described.
We have developed an "inverted" technique for the treatment of these lesions, derived from the usual provisional T stenting. We implant the stent from the proximal main branch through the SB, with reopening of the strut through the distal main branch (DMB) and systematic final kissing balloon. We retrospectively reviewed results in 40 patients. The procedural success was 100%, no failure was observed to rewire the DMB or perform the kissing balloon, and a second sent was implanted in the DMB in only three patients (7.5%). No death, myocardial infarction, stent thrombosis or repeat revascularisation occurred within the first 30 days of follow-up. At a mean of 22+/-14 months, three patients underwent repeat percutaneous coronary intervention (7.5%), with target lesion restenosis (n=2; 5%), other vessel treated (n=1, 2.5%), target lesion revascularisation (n=1; 2.5%), and target vessel revascularisation (n=1, 2.5%).
The "inverted" provisional T stenting technique was safe and highly effective in the management of Medina 0,0,1 coronary bifurcation lesions. Larger trials are needed before its routine application can be recommended.
孤立的、高分级冠状动脉分叉病变位于分支开口(SB)处(Medina 0,0,1 型)较为少见,其具体治疗方法尚未描述。
我们开发了一种“倒置”技术来治疗这些病变,该技术源自常规的临时 T 支架置入术。我们从近端主支经 SB 植入支架,通过远端主支(DMB)和系统的最终对吻球囊扩张来重新开放支架的支撑。我们回顾性分析了 40 例患者的结果。手术成功率为 100%,无重新进入 DMB 或进行对吻球囊扩张失败的情况,仅有 3 例(7.5%)患者需要在 DMB 中植入第二枚支架。在随访的前 30 天内,无死亡、心肌梗死、支架血栓形成或再次血运重建发生。平均随访 22+/-14 个月,3 例患者再次行经皮冠状动脉介入治疗(7.5%),其中靶病变再狭窄(n=2;5%)、其他血管病变治疗(n=1,2.5%)、靶病变血运重建(n=1,2.5%)和靶血管血运重建(n=1,2.5%)。
“倒置”临时 T 支架置入术治疗 Medina 0,0,1 型冠状动脉分叉病变安全且效果显著。在常规应用之前,需要进行更大规模的试验。