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Hard luck stories: the reality of endothelial progenitor cells continues to fall short of the promise.

作者信息

Deb Arjun, Patterson Cam

出版信息

Circulation. 2010 Feb 23;121(7):850-2. doi: 10.1161/CIR.0b013e3181d4c360. Epub 2010 Feb 8.

DOI:10.1161/CIR.0b013e3181d4c360
PMID:20142453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4084608/
Abstract
摘要

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本文引用的文献

1
Circulating endothelial progenitor cells do not contribute to plaque endothelium in murine atherosclerosis.循环内皮祖细胞不会促进小鼠动脉粥样硬化斑块中的内皮细胞。
Circulation. 2010 Feb 23;121(7):898-905. doi: 10.1161/CIRCULATIONAHA.109.885459. Epub 2010 Feb 8.
2
Paracrine mechanisms in adult stem cell signaling and therapy.成体干细胞信号传导与治疗中的旁分泌机制。
Circ Res. 2008 Nov 21;103(11):1204-19. doi: 10.1161/CIRCRESAHA.108.176826.
3
The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models.白细胞亚群对动脉粥样硬化的多方面贡献：来自小鼠模型的经验教训。
Nat Rev Immunol. 2008 Oct;8(10):802-15. doi: 10.1038/nri2415.
4
Assessing identity, phenotype, and fate of endothelial progenitor cells.评估内皮祖细胞的特性、表型和命运。
Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1584-95. doi: 10.1161/ATVBAHA.107.155960. Epub 2008 Jul 31.
5
Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines.具有心脏保护作用的c-kit+细胞来源于骨髓，并调节心肌血管生成细胞因子的平衡。
J Clin Invest. 2006 Jul;116(7):1865-77. doi: 10.1172/JCI27019.
6
Extracardiac progenitor cells repopulate most major cell types in the transplanted human heart.心外祖细胞可重新填充移植入的人类心脏中的大多数主要细胞类型。
Circulation. 2005 Nov 8;112(19):2951-8. doi: 10.1161/CIRCULATIONAHA.105.576017.
7
Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells.定义内皮祖细胞的未解决问题、不断变化的定义和新范式。
Blood. 2005 Sep 1;106(5):1525-31. doi: 10.1182/blood-2005-04-1509. Epub 2005 May 19.
8
Transplantation of bone marrow-derived mononuclear cells in ischemic apolipoprotein E-knockout mice accelerates atherosclerosis without altering plaque composition.将骨髓来源的单核细胞移植到缺血性载脂蛋白E基因敲除小鼠体内可加速动脉粥样硬化，且不改变斑块成分。
Circulation. 2003 Dec 9;108(23):2839-42. doi: 10.1161/01.CIR.0000106161.43954.DF. Epub 2003 Dec 1.
9
Aging, progenitor cell exhaustion, and atherosclerosis.衰老、祖细胞耗竭与动脉粥样硬化。
Circulation. 2003 Jul 29;108(4):457-63. doi: 10.1161/01.CIR.0000082924.75945.48. Epub 2003 Jul 14.
10
Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis.血管病变的心脏移植患者血液中的内皮祖细胞减少，且移植动脉粥样硬化中富含非心脏来源的内皮细胞。
Circulation. 2003 Jul 15;108(2):143-9. doi: 10.1161/01.CIR.0000081703.34526.5D. Epub 2003 Jun 30.