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以急性肾衰竭为表现的维生素D中毒

Vitamin D intoxication presenting as acute renal failure.

作者信息

Naik M A, Banday K A, Najar M S, Reshi A R, Bhat M A

机构信息

Department of Nephrology, Sher-I-Kashmir Institute of Medical Sceinces, Soura, Srinagar, India.

出版信息

Indian J Nephrol. 2008 Jul;18(3):125-6. doi: 10.4103/0971-4065.43693.

DOI:10.4103/0971-4065.43693
PMID:20142919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2813130/
Abstract

A 70 year-old male presented with acute renal failure and mental obtundation. On examination, he was found to have hypercalcemia and on further questioning, it was found that it was secondary to injections of a slow-release vitamin D preparation. Although total body exposure is sufficient for vitamin D synthesis, increased vitamin D deficiency secondary to poor exposure to sunlight is observed in some parts of the world. We report here a case of vitamin D intoxication from the Kashmir valley where vitamin D deficiency is 100% in the general population that is confined indoors.

摘要

一名70岁男性出现急性肾衰竭和精神迟钝。检查时发现他有高钙血症,进一步询问后发现这是由于注射了一种缓释维生素D制剂所致。尽管全身暴露足以合成维生素D,但在世界某些地区,因阳光照射不足继发的维生素D缺乏有所增加。我们在此报告一例来自克什米尔山谷的维生素D中毒病例,该地区一般人群中维生素D缺乏率达100%,这些人都被限制在室内。

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本文引用的文献

1
Vitamin D status in apparently healthy adults in Kashmir Valley of Indian subcontinent.印度次大陆克什米尔山谷地区表面健康成年人的维生素D状况。
Postgrad Med J. 2007 Nov;83(985):713-6. doi: 10.1136/pgmj.2007.059113.
2
[Severe hypercalcemia due to vitamin D intoxication].维生素D中毒所致严重高钙血症
Arch Pediatr. 2007 Nov;14(11):1328-32. doi: 10.1016/j.arcped.2007.08.005. Epub 2007 Oct 10.
3
Dietary supplement-induced vitamin D intoxication.膳食补充剂引起的维生素D中毒。
N Engl J Med. 2007 Jul 19;357(3):308-9. doi: 10.1056/NEJMc063341.
4
Acute vitamin D intoxication in a child.一名儿童的急性维生素D中毒
Pediatrics. 2005 Sep;116(3):e453-6. doi: 10.1542/peds.2004-2580.
5
[Long-term outcomes after acute vitamin D3 intoxication].急性维生素D3中毒后的长期结局
Vopr Pitan. 2004;73(4):11-3.
6
Unusual cases of chronic intoxication by vitamin D.维生素D慢性中毒的罕见病例。
J Nephrol. 2003 Nov-Dec;16(6):917-21.
7
Iatrogenic hypercalcemia due to vitamin D3 ointment (1,24(OH)2D3) combined with thiazide diuretics in a case of psoriasis.
J Dermatol. 2003 Nov;30(11):801-4. doi: 10.1111/j.1346-8138.2003.tb00481.x.
8
Vitamin D intoxication associated with an over-the-counter supplement.与非处方补充剂相关的维生素D中毒。
N Engl J Med. 2001 Jul 5;345(1):66-7. doi: 10.1056/NEJM200107053450115.
9
McCollum Award Lecture, 1994: vitamin D--new horizons for the 21st century.1994年麦科勒姆奖讲座:维生素D——21世纪的新视野
Am J Clin Nutr. 1994 Oct;60(4):619-30. doi: 10.1093/ajcn/60.4.619.
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Symptomatic hypercalcaemia due to vitamin D intoxication.
J Assoc Physicians India. 1991 Dec;39(12):972.