Yadalam Umesh, Kranti K, Seshan Hema
Ex-Postgraduate Student, Department of Periodontics, M.S. Ramaiah Dental College and Hospital, MSRIT Post, Bangalore - 560 054, India.
J Indian Soc Periodontol. 2008 Jan;12(1):26-7. doi: 10.4103/0972-124X.44095.
Glanzmann's thrombasthenia (GT) was reported and described as a bleeding diathesis seen in children and characterized by diminished clot retraction. The disorder is caused by a deficiency in the platelet membrane glycoprotein IIb-IIIa complex, with bleeding due to defective platelet hemostatic plug formation. The recurrent features of GT include purpura, epistaxis, gingival hemorrhage, and menorrhagia. GT being an autosomal recessive trait is reported to be especially prevalent in populations where intermarriage is common. Typically, the patients are diagnosed in infancy within the age of five. Though no differences appear to occur based on sex men more frequently present with gingival bleeding. We report the case of a female patient with GT who presented with the chief complaint of gingival bleeding. The patient was given periodontal treatment under platelet transfusion followed by proper oral hygiene instructions. The report discusses periodontal consideration for GT patients.
血小板无力症（GT）最早被报道并描述为一种在儿童中出现的出血素质，其特征为血块回缩减弱。该病症由血小板膜糖蛋白IIb-IIIa复合物缺乏引起，因血小板止血栓形成缺陷而导致出血。GT的反复出现的特征包括紫癜、鼻出血、牙龈出血和月经过多。据报道，GT作为一种常染色体隐性性状，在近亲结婚普遍的人群中尤为常见。通常，患者在五岁以内的婴儿期被诊断出来。虽然基于性别似乎没有差异，但男性牙龈出血更为常见。我们报告了一例以牙龈出血为主诉的女性GT患者。该患者在输注血小板的情况下接受了牙周治疗，随后接受了适当的口腔卫生指导。本报告讨论了GT患者的牙周问题。
