Kantarci A, Cebeci I, Firatli E, Atamer T, Tuncer O
Department of Periodontology, Faculty of Dentistry, University of Istanbul, Turkey.
J Periodontol. 1996 Aug;67(8):816-20. doi: 10.1902/jop.1996.67.8.816.
Glanzmann's thrombasthenia was reported and described as a bleeding diathesis seen in children and characterized by diminished clot retraction. It is an autosomal recessive bleeding disorder. The disease is marked by frequent mucocutaneous hemorrhages either due to defective function of the platelets or lack of fibrinogen binding membrane receptor glycoproteins IIb/IIIa which are located on the surface of the platelets. Case reports on 3 siblings, a girl of 11, and 2 boys of 12 and 16 years old with Glanzmann's thrombasthenia are reviewed. The major complaint of the patients was gingival bleeding. Periodontal treatment was performed under platelet transfusion and proper oral hygiene instruction was given. The patients were followed for 6 months and no periodontal complications developed during this time. Proper periodontal care for such patients is essential both for local and systemic health.
Glanzmann血小板无力症被报道并描述为一种在儿童中出现的出血素质，其特征为血块收缩减弱。它是一种常染色体隐性出血性疾病。该疾病的特点是由于血小板功能缺陷或血小板表面缺乏纤维蛋白原结合膜受体糖蛋白IIb/IIIa而频繁发生黏膜皮肤出血。本文回顾了3例患有Glanzmann血小板无力症的兄弟姐妹的病例报告，其中包括一名11岁女孩以及两名分别为12岁和16岁的男孩。患者的主要主诉为牙龈出血。在输注血小板的情况下进行了牙周治疗，并给予了适当的口腔卫生指导。对患者进行了6个月的随访，在此期间未出现牙周并发症。对此类患者进行适当的牙周护理对局部和全身健康都至关重要。
