Tsvetkova V
Curr Med Res Opin. 1977;4(9):635-9. doi: 10.1185/03007997709115283.
In order to assess the effect of ACTH on the adrenal cortex when used as a therapeutic or diagnostic agent, adrenocortical function was tested before and 2 hours after 0.5 mg tetracosactrin given intramuscularly in 31 healthy children, divided into 4 groups according to age and sex. Mean plasma cortisol levels were shown to be 184% higher than baseline values after administration of the drug, and there were no significant differences related to age or sex. It is suggested that this simple test can be of practical value in the diagnosis of adrenocortical function in young people.
为了评估促肾上腺皮质激素（ACTH）作为治疗或诊断药物使用时对肾上腺皮质的影响，对31名健康儿童进行了研究。这些儿童根据年龄和性别分为4组，在肌肉注射0.5毫克二十四肽促皮质素前及注射后2小时测试肾上腺皮质功能。给药后平均血浆皮质醇水平比基线值高出184%，且与年龄或性别无关，无显著差异。建议这种简单的测试对青少年肾上腺皮质功能的诊断具有实际价值。
