Faculty of Science, Department of Biology, Basic & Industrial Microbiology Section, Ege University, Bornova, Turkey.
Mycopathologia. 2010 May;169(5):365-72. doi: 10.1007/s11046-010-9275-8. Epub 2010 Feb 9.
The aim of this study was to determine Candida spp. incidence in the oral cavity of denture wearers and characterize predisposing factors in denture-related stomatitis (DRS). Three groups of denture wearers and a control group were evaluated for DRS according to Newton's classification. The amount of yeast in saliva and the presence of yeast on mucosal surfaces were determined by phenotyping methods, and the impact of some risk factors on candidal carriage was evaluated. The development of DRS is most common in complete prosthesis users. When the count of yeast in saliva is >or=400 cfu/ml, the frequency of DRS is increased. In individuals who develop DRS, the most frequently encountered species that was identified as C. albicans. Prosthetic hygiene was related to the intensity of candidal growth and the development of DRS. C. albicans live as saprophyte in the oral cavity. But, it is capable of causing infection if there are predisposing conditions related to the host. Usage of removable prosthesis may cause these microorganisms to gain pathogenicity.
本研究旨在确定戴义齿者口腔中念珠菌属的发生率,并分析与义齿性口炎(DRS)相关的易感因素。根据 Newton 分类法,评估了三组义齿佩戴者和一组对照组的 DRS。通过表型方法确定唾液中酵母的数量和黏膜表面酵母的存在,并评估一些危险因素对念珠菌定植的影响。DRS 最常发生在全口义齿使用者中。当唾液中酵母的计数> = 400 cfu/ml 时,DRS 的发生频率增加。在发生 DRS 的个体中,最常发现的物种是白色念珠菌。义齿卫生与念珠菌生长强度和 DRS 的发生有关。白色念珠菌作为口腔中的腐生物生存,但如果存在与宿主相关的易感条件,它就有能力引起感染。可摘义齿的使用可能会使这些微生物获得致病性。