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[冬眠地松鼠诱导苏醒过程中蛋白质的氧化修饰及血液抗氧化活性]

[Oxidative modification of proteins and antioxidative blood activity of ground squirrels during induced awakening from winter sleep].

作者信息

Astaeva M D, Klichkhanov N K

出版信息

Izv Akad Nauk Ser Biol. 2009 Nov-Dec(6):662-8.

Abstract

The intensity of oxidative modification of plasma proteins and activity of the antioxidative system of the blood of the ground squirrels during awakening from winter sleep is studied. During waking of animals, processes of oxidative modification of proteins in the blood plasma intensify. While the body temperature rises, the antioxidative activity of hydrophylic components of the blood plasma grows essentially, and erythrocyte superoxide dismutase too. Activity of erythrocyte catalase at all stages of waking is definitely higher than in the control. The received results evidence that the high activity of various links of antioxidative blood protection provides stability to oxidative stress during waking of animals from deep sleep.

摘要

研究了地松鼠从冬眠苏醒过程中血浆蛋白的氧化修饰强度和血液抗氧化系统的活性。在动物苏醒期间,血浆中蛋白质的氧化修饰过程加剧。随着体温升高,血浆亲水成分的抗氧化活性显著增强,红细胞超氧化物歧化酶的活性也增强。在苏醒的各个阶段,红细胞过氧化氢酶的活性肯定高于对照组。所得结果表明,血液抗氧化保护各环节的高活性为动物从深度睡眠苏醒期间的氧化应激提供了稳定性。

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