果糖基氨基酸氧化酶工程研究综述：洞察糖化血红蛋白生物传感的未来
Review of fructosyl amino acid oxidase engineering research: a glimpse into the future of hemoglobin A1c biosensing.
作者信息
Ferri Stefano, Kim Seungsu, Tsugawa Wakako, Sode Koji
机构信息
Department of Biotechnology, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan.
出版信息
J Diabetes Sci Technol. 2009 May 1;3(3):585-92. doi: 10.1177/193229680900300324.
Abstract
Glycated proteins, particularly glycated hemoglobin A1c, are important markers for assessing the effectiveness of diabetes treatment. Convenient and reproducible assay systems based on the enzyme fructosyl amino acid oxidase (FAOD) have become attractive alternatives to conventional detection methods. We review the available FAOD-based assays for measurement of glycated proteins as well as the recent advances and future direction of FAOD research. Future research is expected to lead to the next generation of convenient, simple, and economical sensors for glycated protein, ideally suited for point-of-care treatment and self-monitoring applications.
摘要
糖化蛋白，尤其是糖化血红蛋白A1c，是评估糖尿病治疗效果的重要指标。基于果糖基氨基酸氧化酶（FAOD）的便捷且可重复的检测系统已成为传统检测方法的有吸引力的替代方案。我们综述了现有的基于FAOD的糖化蛋白检测方法以及FAOD研究的最新进展和未来方向。未来的研究有望带来下一代便捷、简单且经济的糖化蛋白传感器，非常适合即时护理治疗和自我监测应用。
相似文献
1
Review of fructosyl amino acid oxidase engineering research: a glimpse into the future of hemoglobin A1c biosensing.果糖基氨基酸氧化酶工程研究综述：洞察糖化血红蛋白生物传感的未来
J Diabetes Sci Technol. 2009 May 1;3(3):585-92. doi: 10.1177/193229680900300324.
2
Advancing the development of glycated protein biosensing technology: next-generation sensing molecules.推动糖化蛋白生物传感技术的发展：下一代传感分子。
J Diabetes Sci Technol. 2015 Mar;9(2):183-91. doi: 10.1177/1932296814565784. Epub 2015 Jan 26.
3
Determination of glycated hemoglobin with special emphasis on biosensing methods.糖化血红蛋白的测定，特别着重于生物传感方法。
Anal Biochem. 2014 Jan 1;444:47-56. doi: 10.1016/j.ab.2013.09.023. Epub 2013 Oct 1.
4
Gold Nanostar Colorimetric Detection of Fructosyl Valine as a Potential Future Point of Care Biosensor Candidate for Glycated Haemoglobin Detection.金纳米星比色法检测果糖基缬氨酸，有望成为糖化血红蛋白检测的即时检测生物传感器候选物。
Biosensors (Basel). 2019 Aug 14;9(3):100. doi: 10.3390/bios9030100.
5
Use of fructosyl peptide oxidase for HbA1c assay.果糖基肽氧化酶在糖化血红蛋白（HbA1c）检测中的应用。
J Diabetes Sci Technol. 2015 Mar;9(2):200-5. doi: 10.1177/1932296815569573. Epub 2015 Jan 28.
6
An amperometric biosensor for specific detection of glycated hemoglobin based on recombinant engineered fructosyl peptide oxidase.基于重组工程化果糖基肽氧化酶的糖化血红蛋白特异性检测安培生物传感器。
Int J Biol Macromol. 2020 Jan 1;142:855-865. doi: 10.1016/j.ijbiomac.2019.10.025. Epub 2019 Oct 14.
7
Development of a flow-injection analysis (FIA) enzyme sensor for fructosyl amine monitoring.用于监测果糖基胺的流动注射分析（FIA）酶传感器的研制。
Anal Bioanal Chem. 2002 Jul;373(4-5):211-4. doi: 10.1007/s00216-002-1319-6. Epub 2002 Jun 6.
8
An amperometric hemoglobin A1c biosensor based on immobilization of fructosyl amino acid oxidase onto zinc oxide nanoparticles-polypyrrole film.基于将果糖基氨基酸氧化酶固定在氧化锌纳米粒子-聚吡咯膜上的安培法糖化血红蛋白 A1c 生物传感器。
Anal Biochem. 2012 Nov 15;430(2):156-62. doi: 10.1016/j.ab.2012.08.002. Epub 2012 Aug 18.
9
Affinity sensor for haemoglobin A1c based on single-walled carbon nanotube field-effect transistor and fructosyl amino acid binding protein.基于单壁碳纳米管场效应晶体管和果糖基氨基酸结合蛋白的血红蛋白 A1c 亲和传感器。
Biosens Bioelectron. 2019 Mar 15;129:254-259. doi: 10.1016/j.bios.2018.09.069. Epub 2018 Sep 20.
10
A Review of Electrochemical Sensors for the Detection of Glycated Hemoglobin.电化学传感器用于糖化血红蛋白检测的研究进展。
Biosensors (Basel). 2022 Apr 8;12(4):221. doi: 10.3390/bios12040221.
引用本文的文献
1
Glycemic Control and Cardiometabolic Risk in Black Zimbabweans with Type 2 Diabetes Mellitus.津巴布韦黑人2型糖尿病患者的血糖控制与心脏代谢风险
Diabetes Metab Syndr Obes. 2024 Aug 27;17:3187-3196. doi: 10.2147/DMSO.S473042. eCollection 2024.
2
Fructosyl Amino Oxidase as a Therapeutic Enzyme in Age-Related Macular Degeneration.糖基氨基酸氧化酶作为与年龄相关的黄斑变性的治疗性酶。
Int J Mol Sci. 2024 Apr 27;25(9):4779. doi: 10.3390/ijms25094779.
3
Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition.为增强稳定性和扩大底物识别范围而定制 FPOX 酶。
Sci Rep. 2023 Oct 30;13(1):18610. doi: 10.1038/s41598-023-45428-1.
4
Enzymatic Deglycation of Damaged Skin by Means of Combined Treatment of Fructosamine-3-Kinase and Fructosyl-Amino Acid Oxidase.通过联合使用果糖胺-3-激酶和果糖基氨基酸氧化酶对受损皮肤进行酶促去糖基化。
Int J Mol Sci. 2023 May 19;24(10):8981. doi: 10.3390/ijms24108981.
5
Topical Application of Deglycating Enzymes as an Alternative Non-Invasive Treatment for Presbyopia.去糖基化酶的局部应用作为一种非侵入性治疗老视的替代方法。
Int J Mol Sci. 2023 Apr 16;24(8):7343. doi: 10.3390/ijms24087343.
6
A Review of Electrochemical Sensors for the Detection of Glycated Hemoglobin.电化学传感器用于糖化血红蛋白检测的研究进展。
Biosensors (Basel). 2022 Apr 8;12(4):221. doi: 10.3390/bios12040221.
7
Bright Side of : Secondary Metabolites Bioactivities and Industrial Relevance in Biotechnology and Nanotechnology.《次生代谢产物的生物活性及其在生物技术和纳米技术中的工业相关性的光明面》
J Fungi (Basel). 2021 Nov 8;7(11):943. doi: 10.3390/jof7110943.
8
Tobacco Root Endophytic Harbors Genomic Features Enabling the Catabolism of Host-Specific Plant Specialized Metabolites.烟草根内生菌蕴藏着使宿主特异性植物次生代谢物发生代谢的基因组特征。
mBio. 2021 Jun 29;12(3):e0084621. doi: 10.1128/mBio.00846-21. Epub 2021 May 28.
9
Recent Trends in Electrochemical Sensors for Vital Biomedical Markers Using Hybrid Nanostructured Materials.使用混合纳米结构材料的用于重要生物医学标志物的电化学传感器的最新趋势。
Adv Sci (Weinh). 2020 May 12;7(13):1902980. doi: 10.1002/advs.201902980. eCollection 2020 Jul.
10
Gold Nanostar Colorimetric Detection of Fructosyl Valine as a Potential Future Point of Care Biosensor Candidate for Glycated Haemoglobin Detection.金纳米星比色法检测果糖基缬氨酸，有望成为糖化血红蛋白检测的即时检测生物传感器候选物。
Biosensors (Basel). 2019 Aug 14;9(3):100. doi: 10.3390/bios9030100.
本文引用的文献
1
Standards of medical care in diabetes--2009.《糖尿病医疗护理标准——2009》
Diabetes Care. 2009 Jan;32 Suppl 1(Suppl 1):S13-61. doi: 10.2337/dc09-S013.
2
Crystal structure of the deglycating enzyme fructosamine oxidase (amadoriase II).去糖化酶果糖胺氧化酶（氨基脱氧酮糖还原酶II）的晶体结构
J Biol Chem. 2008 Oct 3;283(40):27007-16. doi: 10.1074/jbc.M804885200. Epub 2008 Jul 30.
3
Direct enzymatic assay for %HbA1c in human whole blood samples.人全血样本中糖化血红蛋白A1c（HbA1c）百分比的直接酶法测定。
Clin Biochem. 2008 May;41(7-8):576-83. doi: 10.1016/j.clinbiochem.2008.01.013. Epub 2008 Jan 31.
4
Enhancement of thermostability of fungal deglycating enzymes by directed evolution.通过定向进化提高真菌去糖基化酶的热稳定性。
Appl Microbiol Biotechnol. 2008 Apr;78(5):775-81. doi: 10.1007/s00253-008-1363-z. Epub 2008 Feb 1.
5
Development of fructosyl amine oxidase specific to fructosyl valine by site-directed mutagenesis.通过定点诱变开发对果糖基缬氨酸具有特异性的果糖基胺氧化酶。
Protein Eng Des Sel. 2008 Apr;21(4):233-9. doi: 10.1093/protein/gzm047. Epub 2008 Jan 31.
6
Alteration of substrate specificity of fructosyl-amino acid oxidase from Fusarium oxysporum.尖孢镰刀菌果糖基氨基酸氧化酶底物特异性的改变。
Appl Microbiol Biotechnol. 2007 Mar;74(4):813-9. doi: 10.1007/s00253-006-0720-z. Epub 2006 Dec 9.
7
Alteration of substrate specificity of fructosyl-amino acid oxidase from Ulocladium sp. JS-103.来自链格孢属菌株JS-103的果糖基氨基酸氧化酶底物特异性的改变。
J Biosci Bioeng. 2006 Sep;102(3):241-3. doi: 10.1263/jbb.102.241.
8
Active site analysis of fructosyl amine oxidase using homology modeling and site-directed mutagenesis.
Biotechnol Lett. 2006 Dec;28(23):1895-900. doi: 10.1007/s10529-006-9173-9. Epub 2006 Oct 17.
9
Novel fluorescent sensing system for alpha-fructosyl amino acids based on engineered fructosyl amino acid binding protein.基于工程化果糖基氨基酸结合蛋白的新型α-果糖基氨基酸荧光传感系统。
Biosens Bioelectron. 2007 Apr 15;22(9-10):1933-8. doi: 10.1016/j.bios.2006.08.022. Epub 2006 Oct 2.
10
SocA is a novel periplasmic binding protein for fructosyl amino acid.SocA是一种新型的果糖基氨基酸周质结合蛋白。
Biochem Biophys Res Commun. 2005 Nov 4;336(4):1074-80. doi: 10.1016/j.bbrc.2005.08.230.
Zotero 插件