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《次生代谢产物的生物活性及其在生物技术和纳米技术中的工业相关性的光明面》

Bright Side of : Secondary Metabolites Bioactivities and Industrial Relevance in Biotechnology and Nanotechnology.

作者信息

Ibrahim Sabrin R M, Sirwi Alaa, Eid Basma G, Mohamed Shaimaa G A, Mohamed Gamal A

机构信息

Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi Arabia.

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.

出版信息

J Fungi (Basel). 2021 Nov 8;7(11):943. doi: 10.3390/jof7110943.

Abstract

Fungi have been assured to be one of the wealthiest pools of bio-metabolites with remarkable potential for discovering new drugs. The pathogenic fungi, affects many valuable trees and crops all over the world, producing wilt. This fungus is a source of different enzymes that have variable industrial and biotechnological applications. Additionally, it is widely employed for the synthesis of different types of metal nanoparticles with various biotechnological, pharmaceutical, industrial, and medicinal applications. Moreover, it possesses a mysterious capacity to produce a wide array of metabolites with a broad spectrum of bioactivities such as alkaloids, jasmonates, anthranilates, cyclic peptides, cyclic depsipeptides, xanthones, quinones, and terpenoids. Therefore, this review will cover the previously reported data on , especially its metabolites and their bioactivities, as well as industrial relevance in biotechnology and nanotechnology in the period from 1967 to 2021. In this work, 180 metabolites have been listed and 203 references have been cited.

摘要

真菌已被确认为生物代谢产物最丰富的宝库之一,在发现新药方面具有巨大潜力。这种致病真菌影响着世界各地许多有价值的树木和作物,导致枯萎病。这种真菌是多种酶的来源,这些酶具有不同的工业和生物技术应用。此外,它还被广泛用于合成不同类型的金属纳米颗粒,具有各种生物技术、制药、工业和医学应用。此外,它具有神秘的能力,能产生一系列具有广泛生物活性的代谢产物,如生物碱、茉莉酸酯、邻氨基苯甲酸酯、环肽、环缩肽、呫吨酮、醌和萜类化合物。因此,本综述将涵盖此前报道的关于[此处原文缺失真菌名称]的数据,特别是其代谢产物及其生物活性,以及1967年至2021年期间在生物技术和纳米技术方面的工业相关性。在这项工作中,列出了180种代谢产物,并引用了203篇参考文献。

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