果糖基肽氧化酶在糖化血红蛋白（HbA1c）检测中的应用。
Use of fructosyl peptide oxidase for HbA1c assay.
作者信息
Yonehara Satoshi, Inamura Norio, Fukuda Miho, Sugiyama Koji
机构信息
ARKRAY, Inc., Kyoto, Japan
ARKRAY, Inc., Kyoto, Japan.
出版信息
J Diabetes Sci Technol. 2015 Mar;9(2):200-5. doi: 10.1177/1932296815569573. Epub 2015 Jan 28.
Abstract
ARKRAY, Inc developed the world's first automatic glycohemoglobin analyzer based on HPLC (1981). After that, ARKRAY developed enzymatic HbA1c assay "CinQ HbA1c" with the spread and diversification of HbA1c measurement (2007). CinQ HbA1c is the kit of Clinical Chemistry Analyzer, which uses fructosyl peptide oxidase (FPOX) for a measurement reaction. This report mainly indicates the developmental background, measurement principle, and future of the enzymatic method HbA1c reagent.
摘要
爱科来公司于1981年研发出世界上首款基于高效液相色谱法的自动糖化血红蛋白分析仪。此后，随着糖化血红蛋白检测的普及和多样化，爱科来又研发出酶促糖化血红蛋白检测法“CinQ HbA1c”（2007年）。CinQ HbA1c是临床化学分析仪的试剂盒，其测量反应采用果糖基肽氧化酶（FPOX）。本报告主要介绍酶促法糖化血红蛋白试剂的研发背景、测量原理及未来发展。
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