Division of Angiology, Department of Internal Medicine II, Medical University Vienna, Vienna General Hospital, Vienna, Austria.
Microvasc Res. 2010 Jul;80(1):54-7. doi: 10.1016/j.mvr.2010.01.010. Epub 2010 Feb 6.
We aimed to investigate the correlation of infrared thermography (IT) with laser Doppler perfusion imager (LDPI) among patients with primary Raynaud's phenomenon and healthy controls.
Forty-seven individuals were included: we examined 25 patients with primary Raynaud's phenomenon and 22 age and gender matched healthy controls. IT of the volar surface of the subjects' left hands was performed to record skin temperature while skin perfusion of the same area was determined using LDPI. All measurements were obtained at room temperature (baseline measurements) and following standardized cold provocation.
Good correlation of baseline measurements was found between IT and LDPI in primary Raynaud patients and healthy controls (r=0.868, p<0.0001 vs. r=0.790, p<0.0001). Following cold challenge, correlation was weaker in both groups (r=0.742 vs. r=0.766, p<0.0001). Correlation after cold provocation was statistically significant among patients with primary Raynaud's phenomenon in contrast to controls (Chi Quadrat, p=0.023 vs. p=0.306).
A significant correlation was found between IT and LDPI in primary Raynaud patients and in healthy controls (r=0.868 and r=0.742, both p<0.0001). Following cold provocation, correlation decreases in both groups. Thus, at room temperature IT might substitute for skin perfusion measured by LDPI.
我们旨在研究原发性雷诺现象患者与健康对照者之间红外热成像（IT）与激光多普勒血流成像（LDPI）的相关性。
共纳入 47 名个体：我们检查了 25 例原发性雷诺现象患者和 22 名年龄和性别匹配的健康对照者。对受试者左手掌侧进行 IT 以记录皮肤温度，同时使用 LDPI 测定同一区域的皮肤灌注。所有测量均在室温下（基线测量）和标准化冷刺激后进行。
原发性雷诺病患者和健康对照者的 IT 与 LDPI 之间在基线测量时具有良好的相关性（r=0.868，p<0.0001 与 r=0.790，p<0.0001）。在冷刺激后，两组的相关性均减弱（r=0.742 与 r=0.766，p<0.0001）。与对照组相比，原发性雷诺病患者在冷刺激后相关性具有统计学意义（卡方检验，p=0.023 与 p=0.306）。
原发性雷诺病患者和健康对照者的 IT 与 LDPI 之间存在显著相关性（r=0.868 和 r=0.742，均 p<0.0001）。在冷刺激后，两组的相关性均减弱。因此，在室温下，IT 可能替代 LDPI 测量的皮肤灌注。
