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孕期暴露于电离辐射:对致畸风险及结局的认知

Exposure to ionizing radiation during pregnancy: perception of teratogenic risk and outcome.

作者信息

Bentur Y, Horlatsch N, Koren G

机构信息

Motherisk Program, Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

Teratology. 1991 Feb;43(2):109-12. doi: 10.1002/tera.1420430203.

DOI:10.1002/tera.1420430203
PMID:2014476
Abstract

We quantified the perception of teratogenic risk in women attending the Motherisk program for counseling about diagnostic radiation in pregnancy (n = 50) and compared it with a control group of women exposed to nonteratogenic drugs and chemicals (n = 48). Before receiving known information about the specific exposure, women exposed to radiation assigned themselves a significantly higher teratogenic risk compared with the control group (25.5 +/- 4.3% versus 15.7 +/- 3.0% for major malformations, P less than 0.01). The post-consultation perception of teratogenic risk did not differ between the two groups. Special consideration and attention should be given when counseling pregnant women exposed to low-dose ionizing radiation, as their misperception of teratogenic risk may lead them to unnecessary termination of their pregnancy.

摘要

我们对参加Motherisk项目咨询孕期诊断性辐射相关事宜的女性(n = 50)的致畸风险认知进行了量化,并将其与接触非致畸性药物和化学物质的女性对照组(n = 48)进行了比较。在获得关于特定暴露的已知信息之前,与对照组相比,接触辐射的女性给自己分配的致畸风险显著更高(主要畸形的风险分别为25.5±4.3%和15.7±3.0%,P<0.01)。两组在咨询后对致畸风险的认知没有差异。在为接触低剂量电离辐射的孕妇提供咨询时,应给予特别的考虑和关注,因为她们对致畸风险的错误认知可能导致她们不必要地终止妊娠。

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