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Edema of cornea precipitated by quinacrine (atabrine).由阿的平（奎纳克林）引起的角膜水肿。
Arch Ophthal. 1946 Feb;35:120-34. doi: 10.1001/archopht.1946.00890200125005.
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Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis.来氟米特诱发的类风湿关节炎患者中毒性表皮坏死松解症
Joint Bone Spine. 2008 Oct;75(5):597-9. doi: 10.1016/j.jbspin.2007.08.013. Epub 2008 Sep 20.
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Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial.阿巴西普治疗儿童幼年特发性关节炎：一项随机、双盲、安慰剂对照撤药试验。
Lancet. 2008 Aug 2;372(9636):383-91. doi: 10.1016/S0140-6736(08)60998-8. Epub 2008 Jul 14.
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Stevens Johnson syndrome, toxic epidermal necrolysis and SJS-TEN overlap: a retrospective study of causative drugs and clinical outcome.史蒂文斯-约翰逊综合征、中毒性表皮坏死松解症及史蒂文斯-约翰逊综合征-中毒性表皮坏死松解症重叠综合征：致病药物及临床结局的回顾性研究
Indian J Dermatol Venereol Leprol. 2008 May-Jun;74(3):238-40. doi: 10.4103/0378-6323.41369.
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Chorioretinitis and vitreitis due to Tropheryma whipplei after transplantation: case report and review.移植后由惠普尔嗜组织细胞菌引起的脉络膜视网膜炎和玻璃体炎：病例报告及文献复习
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Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate.阿巴西普或英夫利昔单抗对比安慰剂治疗类风湿关节炎（对甲氨蝶呤反应不足）的疗效与安全性：ATTEST一项III期、多中心、随机、双盲、安慰剂对照研究
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Conjunctival pigmentation in Stevens-Johnson syndrome.史蒂文斯-约翰逊综合征中的结膜色素沉着。
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Efficacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-tumour necrosis factor therapy.类风湿关节炎患者对抗肿瘤坏死因子治疗反应不足，接受选择性共刺激调节剂阿巴西普治疗2年后的疗效和安全性。
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抗风湿药物的眼部副作用：风湿病医生应该知道什么。

Ocular side effects of anti-rheumatic medications: what a rheumatologist should know.

机构信息

Athens Eye Hospital, Second Eye Clinic, Athens, Greece.

出版信息

Lupus. 2010 May;19(6):675-82. doi: 10.1177/0961203309360539. Epub 2010 Feb 9.

DOI:10.1177/0961203309360539
PMID:20144965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2926651/
Abstract

Nearly every drug may cause changes to ocular tissues through a variety of mechanisms. Medication overdoses, drug-drug interactions but also chronic administration of medications at the recommended doses may lead to ocular toxicity. The ocular side effects, screening for eye toxicity and treatment guidelines for anti-inflammatory and immunosuppressive drugs commonly used by rheumatologists are reviewed herein.

摘要

几乎每种药物都可能通过多种机制引起眼组织的改变。药物过量、药物相互作用以及推荐剂量下的药物长期使用都可能导致眼毒性。本文回顾了眼科副作用、眼毒性筛查以及风湿科常用的抗炎和免疫抑制剂的治疗指南。