Martins P, Peña E, Calvo B, Doblaré M, Mascarenhas T, Natal Jorge R, Ferreira A
IDMEC-Polo FEUP, Faculty of Engineering, University of Porto, Porto, Portugal.
Comput Methods Biomech Biomed Engin. 2010 Jun;13(3):327-37. doi: 10.1080/10255840903208197.
The mechanical properties of the vaginal tissue need to be characterised to perform accurate simulations of prolapse and other pelvic disorders that commonly affect women. This is also a fundamental step towards the improvement of therapeutic techniques such as surgery. Issues like the efficiency of using autologous tissue in pelvic reconstruction may be addressed. The goal of this study was to characterise the elastic behaviour of vaginal tissue. For this purpose, prolapsed vaginal tissue from eight different post-menopausal patients, excised during prolapse corrective surgery, was mechanically tested. The mechanical testing of vaginal tissue, consisting of uniaxial tension tests performed along the longitudinal axis of the vagina, revealed the nonlinear mechanical behaviour of the tissue. The material model parameters were fit to the experimental data using the Levenberg-Marquardt optimisation algorithm. All the curve fittings showed a good agreement between experimental and theoretical results, evidenced by R² values close to 1 and by very low ε values.
为了准确模拟通常影响女性的脱垂和其他盆腔疾病，需要对阴道组织的力学特性进行表征。这也是改进诸如手术等治疗技术的基本步骤。骨盆重建中使用自体组织的效率等问题可能会得到解决。本研究的目的是表征阴道组织的弹性行为。为此，对八名不同绝经后患者在脱垂矫正手术中切除的脱垂阴道组织进行了力学测试。阴道组织的力学测试包括沿阴道纵轴进行的单轴拉伸试验，揭示了组织的非线性力学行为。使用Levenberg-Marquardt优化算法将材料模型参数拟合到实验数据中。所有曲线拟合均显示实验结果与理论结果之间具有良好的一致性，R²值接近1且ε值非常低证明了这一点。
