口腔自我检查在高危人群中准确性的初步研究。
Pilot study to estimate the accuracy of mouth self-examination in an at-risk group.
机构信息
Department of Oral Health Services Research and Dental Public Health, Dental Institute, King's College London, Caldecot Road, London, UK.
出版信息
Head Neck. 2010 Oct;32(10):1393-401. doi: 10.1002/hed.21341.
BACKGROUND
Mouth self-examination (MSE) is a possible method of detecting oral cancer early. This study aimed to determine whether those at risk of developing oral cancer are able to correctly detect potentially malignant oral lesions via MSE.
METHODS
Participants (53 smokers aged over 45 years) received an oral mucosal examination by the dentist and then performed MSE after education through a self-read leaflet. The dentist and participant both recorded the presence and absence of potentially malignant oral lesions.
RESULTS
The prevalence of potentially malignant oral lesions was 22%. The sensitivity of MSE was 33% and the specificity was 54%. MSE had a positive predictive value of 17% and a negative predictive value of 73%.
CONCLUSION
The at-risk group were poor at correctly identifying the presence or absence of potentially malignant oral lesions. A leaflet may be an ineffective training tool to aid self-identification of potentially malignant oral lesions.
背景
口腔自我检查（MSE）是早期发现口腔癌的一种可能方法。本研究旨在确定是否存在发生口腔癌风险的人群能够通过 MSE 正确检测出潜在的恶性口腔病变。
方法
参与者（53 名年龄超过 45 岁的吸烟者）接受了牙医进行的口腔黏膜检查，然后通过自我阅读手册进行了 MSE 教育。牙医和参与者都记录了潜在恶性口腔病变的存在和不存在情况。
结果
潜在恶性口腔病变的患病率为 22%。MSE 的敏感性为 33%，特异性为 54%。MSE 的阳性预测值为 17%，阴性预测值为 73%。
结论
高危人群在正确识别潜在恶性口腔病变的存在或不存在方面表现不佳。手册可能是一种无效的培训工具，无法帮助自我识别潜在恶性口腔病变。
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