Huber Michaell A
Department of Dental Diagnostic Science, Division of Oral Medicine, The University of Texas Health Science Center at San Antonio, USA.
Tex Dent J. 2009 Jun;126(6):528-35.
The VELscope is a visualization-enhancement adjunct currently marketed to assist the clinician in assessing potentially dysplastic or malignant mucosal lesions in the oral cavity. The author examined 130 subjects, who smoked at least one package of cigarettes per day. The clinical findings derived from a conventional examination protocol were compared to the findings observed with the VELscope. Ten suspicious lesions were identified by conventional examination. No occult suspicious lesions were identified using the VELscope. VELscope interpretation did not enhance or otherwise alter the clinical management of the suspicious lesions. Several commonly occurring conditions, such as mucosal pigmentations, ulcerations, irritations, and gingivitis were associated with a loss of fluorescence using VELscope. The findings of this study raise questions concerning the utilization of the VELscope as a screening adjunct.
VELscope是一种目前已上市的可视化增强辅助工具，旨在帮助临床医生评估口腔中潜在的发育异常或恶性粘膜病变。作者检查了130名每天至少吸食一包香烟的受试者。将传统检查方案得出的临床结果与使用VELscope观察到的结果进行了比较。通过传统检查发现了10个可疑病变。使用VELscope未发现隐匿性可疑病变。VELscope的解读并未加强或以其他方式改变对可疑病变的临床管理。一些常见情况，如粘膜色素沉着、溃疡、刺激和牙龈炎，与使用VELscope时荧光丧失有关。本研究结果引发了关于将VELscope用作筛查辅助工具的疑问。
