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甲状腺危象合并多器官功能衰竭、弥散性血管内凝血及血清游离三碘甲状腺原氨酸水平正常的中风。

Thyroid storm with multiple organ failure, disseminated intravascular coagulation, and stroke with a normal serum FT3 level.

作者信息

Harada Yuko, Akiyama Hisanao, Yoshimoto Tatsuji, Urao Yasuko, Ryuzaki Munekazu, Handa Michiko

机构信息

Department of Cardiology, Kawasaki Municipal Ida Hospital, Japan.

出版信息

Intern Med. 2012;51(17):2379-83. doi: 10.2169/internalmedicine.51.7974. Epub 2012 Sep 1.

DOI:10.2169/internalmedicine.51.7974
PMID:22975553
Abstract

Thyroid storm is a rare disorder with a sudden onset, rapid progression and high mortality. We experienced a case of thyroid storm which had a devastating course, including multiple organ failure (MOF), severe hypoglycemia, disseminated intravascular coagulation (DIC), and stroke. It was difficult to make a diagnosis of thyroid storm in the present patient, because she did not have a history of thyroid disease and her serum FT3 level was normal. Clinicians should be aware that thyroid storm can occur even when there is an almost normal level of thyroid hormones, and that intensive anticoagulation is required for patients with atrial fibrillation to prevent stroke after thyroid storm.

摘要

甲状腺危象是一种罕见的疾病,起病急骤、进展迅速且死亡率高。我们遇到一例甲状腺危象患者,其病情凶险,出现了多器官功能衰竭(MOF)、严重低血糖、弥散性血管内凝血(DIC)和中风。该患者难以诊断为甲状腺危象,因为她既往无甲状腺疾病史且血清FT3水平正常。临床医生应意识到,即使甲状腺激素水平几乎正常,也可能发生甲状腺危象,并且对于房颤患者,甲状腺危象后需要强化抗凝以预防中风。

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