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健康学龄儿童心房传导阻滞的患病率:通过P波时限或形态学分析进行定义

Prevalence of interatrial block in healthy school-aged children: definition by P-wave duration or morphological analysis.

作者信息

Dilaveris Polychronis, Raftopoulos Leonidas, Giannopoulos Georgios, Katinakis Stylianos, Maragiannis Dimitrios, Roussos Dimitrios, Gatzoulis Konstantinos, Michaelides Andreas, Stefanadis Christodoulos

机构信息

1st University Department of Cardiology, Hippokration Hospital, 22, Miltiadou Str., 15561, Athens, Greece.

出版信息

Ann Noninvasive Electrocardiol. 2010 Jan;15(1):17-25. doi: 10.1111/j.1542-474X.2009.00335.x.

Abstract

BACKGROUND

P waves > or = 110 ms in adults and > or = 90 ms in children are considered abnormal, signifying interatrial block, particularly in the first case.

METHODS

To evaluate the prevalence of interatrial block in healthy school-aged children, we obtained 12-lead digital ECGs (Cardioperfect 1.1, CardioControl NV, Delft, The Netherlands) of 664 healthy children (349 males/315 females, age range 6-14 years old). P-wave analysis indices [mean, maximum and minimum (in the 12 leads) P-wave duration, P-wave dispersion, P-wave morphology in the derived orthogonal (X, Y, Z) leads, as well the amplitude of the maximum spatial P-wave vector] were calculated in all study participants.

RESULTS

P-wave descriptor values were: mean P-wave duration 84.9 + or - 9.5 ms, maximum P-wave duration 99.0 + or - 9.8 ms, P dispersion 32.2 + or - 12.5 ms, spatial P amplitude 182.7 + or - 69.0 microV. P-wave morphology distribution in the orthogonal leads were: Type I 478 (72.0%), Type II 178 (26.8%), Type III 1 (0.2%), indeterminate 7 (1%). Maximum P-wave duration was positively correlated to age (P < 0.001) and did not differ between sexes (P = 0.339). Using the 90-ms value as cutoff for P-wave duration, 502 (75.6%) children would be classified as having maximum P-wave duration above reference range. The 95th and the 99th percentiles were in the overall population 117 ms and 125 ms, respectively. P-wave morphology type was not in any way correlated to P-wave duration (P = 0.715).

CONCLUSIONS

Abnormal P-wave morphology signifying the presence of interatrial block is very rare in a healthy pediatric population, while widened P waves are quite common, although currently classified as abnormal.

摘要

背景

成人P波≥110毫秒、儿童P波≥90毫秒被视为异常,提示存在心房内传导阻滞,尤其是在前一种情况。

方法

为评估健康学龄儿童中心房内传导阻滞的患病率,我们获取了664名健康儿童(349名男性/315名女性,年龄范围6至14岁)的12导联数字心电图(Cardioperfect 1.1,CardioControl NV,荷兰代尔夫特)。计算了所有研究参与者的P波分析指标[平均、最大和最小(12导联)P波持续时间、P波离散度、推导的正交(X、Y、Z)导联中的P波形态以及最大空间P波向量的幅度]。

结果

P波描述值为:平均P波持续时间84.9±9.5毫秒,最大P波持续时间99.0±9.8毫秒,P离散度32.2±12.5毫秒,空间P波幅度182.7±69.0微伏。正交导联中P波形态分布为:I型478例(72.0%),II型178例(26.8%),III型1例(0.2%),不确定型7例(1%)。最大P波持续时间与年龄呈正相关(P<0.001),且在性别间无差异(P=0.339)。以90毫秒作为P波持续时间的截断值,502名(75.6%)儿童的最大P波持续时间将被归类为高于参考范围。总体人群中第95和第99百分位数分别为117毫秒和125毫秒。P波形态类型与P波持续时间无任何相关性(P=0.715)。

结论

在健康儿童人群中,提示存在心房内传导阻滞的异常P波形态非常罕见,而P波增宽相当常见,尽管目前被归类为异常。

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High prevalence of widened P waves among pediatric patients in 2 separate hospitals.两家独立医院的儿科患者中P波增宽的高患病率。
J Electrocardiol. 2008 Jan-Feb;41(1):63-7. doi: 10.1016/j.jelectrocard.2007.02.005. Epub 2007 May 24.
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Reevaluation of the criterion for interatrial block.心房传导阻滞标准的重新评估。
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