Mehrzad Raman, Spodick David H
Department of Medicine, Steward Carney Hospital, Boston, MA, USA;
Department of Medicine, Division of Cardiology, St. Vincent Hospital and University of Massachusetts Medical School, Worcester, MA, USA.
Iran J Med Sci. 2014 Mar;39(2):84-93.
Interatrial block (IAB) denotes a conduction delay between the two atria (P-wave duration ≥110 ms). Depending on the severity of the block, IAB can be partial or advanced. Even though several studies have reported a high prevalence of IAB, it still remains a diagnosis many neglect without any follow-up. The crisis in IAB is undramatic until predictable complications appear. Nevertheless, the danger in IAB is real because of the major associations with multiple medical conditions, including atrial fibrillation, myocardial ischemia, left atrial enlargement, and systemic emboli. There are different treatment options for IAB to eliminate its consequences, including pacing and medical management with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. Pacing has been shown to give promising results and could potentially prevent conditions related to cardiovascular disease such as hypertension or diabetes mellitus. Given the high prevalence of IAB, together with its potentially serious consequences, and yet being largely ignored, we stress attention to this potentially dangerous pandemic and raise consideration for further investigations.
心房传导阻滞（IAB）指的是两心房之间的传导延迟（P波时限≥110毫秒）。根据阻滞的严重程度，IAB可分为不完全性或完全性。尽管多项研究报告了IAB的高患病率，但它仍然是一个许多人忽视且未进行任何随访的诊断。在可预测的并发症出现之前，IAB的病情发展并不明显。然而，由于IAB与多种疾病密切相关，包括心房颤动、心肌缺血、左心房扩大和系统性栓塞，其危险性是真实存在的。对于IAB有不同的治疗选择以消除其后果，包括起搏以及使用血管紧张素转换酶抑制剂和血管紧张素受体阻滞剂进行药物治疗。起搏已显示出有希望的结果，并且有可能预防与心血管疾病相关的病症，如高血压或糖尿病。鉴于IAB的高患病率及其潜在的严重后果，然而却在很大程度上被忽视，我们强调要关注这一潜在的危险疾病，并呼吁考虑进行进一步研究。
