Department of Psychological & Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH 03755, USA.
Soc Cogn Affect Neurosci. 2010 Dec;5(4):363-8. doi: 10.1093/scan/nsq014. Epub 2010 Feb 10.
In this study, we compared the effects of using neutral face masks vs non-face pattern masks on amygdala activity to masked fearful faces. Twenty-seven subjects viewed 18 s blocks of either fearful or happy faces masked with either neutral faces or patterns, while their brain activity was measured using functional magnetic resonance imaging. Results replicated increased amygdala activation to face-masked fearful vs happy faces. In the pattern mask condition, the amygdala discriminated between masked fearful and happy faces, but this effect manifested as a decrease in activation to fearful faces compared to happy faces. This interactive effect between facial expression and mask stimulus shows that amygdala responses to masked fearful faces are influenced by the fearful stimuli per se as well as their interaction with the mask stimulus.
在这项研究中，我们比较了使用中性面罩与非面部图案面罩对杏仁核活动的影响，以屏蔽恐惧面孔。27 名受试者观看了 18 秒的恐惧或快乐面孔的遮挡块，同时使用功能磁共振成像测量他们的大脑活动。结果复制了杏仁核对蒙面恐惧面孔与快乐面孔的激活增加。在图案面罩条件下，杏仁核区分了蒙面的恐惧和快乐面孔，但这种效应表现为与快乐面孔相比，对恐惧面孔的激活减少。这种面部表情和面罩刺激之间的交互作用表明，杏仁核对蒙面恐惧面孔的反应受到恐惧刺激本身以及它们与面罩刺激相互作用的影响。
