Department of Anatomy & Developmental Biology, Monash University Clayton Campus, Melbourne 3800, Victoria, Australia.
Nat Rev Cancer. 2010 Mar;10(3):205-12. doi: 10.1038/nrc2795. Epub 2010 Feb 11.
Breast cancer and prostate cancer are the two most common invasive cancers in women and men, respectively. Although these cancers arise in organs that are different in terms of anatomy and physiological function both organs require gonadal steroids for their development, and tumours that arise from them are typically hormone-dependent and have remarkable underlying biological similarities. Many of the recent advances in understanding the pathophysiology of breast and prostate cancers have paved the way for new treatment strategies. In this Opinion article we discuss some key issues common to breast and prostate cancer and how new insights into these cancers could improve patient outcomes.
乳腺癌和前列腺癌分别是女性和男性中最常见的两种侵袭性癌症。尽管这些癌症发生在解剖和生理功能上不同的器官中，但两者的发育都需要性腺类固醇，而且由此产生的肿瘤通常是激素依赖性的，并具有显著的潜在生物学相似性。对乳腺癌和前列腺癌病理生理学的许多最新研究进展为新的治疗策略铺平了道路。在这篇观点文章中，我们讨论了乳腺癌和前列腺癌的一些共同关键问题，以及对这些癌症的新认识如何改善患者的预后。
