Department of Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
J Hum Hypertens. 2010 Oct;24(10):652-8. doi: 10.1038/jhh.2010.6. Epub 2010 Feb 11.
The aim of the study was to examine the association of a trend in body mass index (BMI) status with current blood pressure in a cohort of school children from South India. A population of 25,228 children was selected using stratified random sampling method. Height and weight were measured in 2003-2004. Height, weight and blood pressure were measured in 2005-2006. A total of 12,129 children aged 5-16 years having paired data were analysed. Blood pressure and BMI values were converted to Z scores using International paediatric reference values. An increase in Z BMI meant that the child is moving to a higher BMI level with respect to his or her age and sex. In the cohort, 62.4% children had a higher Z BMI at follow-up than at baseline. Children with higher Z BMI at follow-up were labelled as positive BMI status group (PBSG) and the remaining as negative BMI status group (NBSG). The positive trend in BMI was more in rural areas, government schools and girls. In all subgroups, PBSG showed significantly higher systolic blood pressures (SBPs) than NBSG. PBSG showed significantly higher diastolic blood pressures (DBPs) in urban area, government schools and girls when compared with NBSG. Prevalence of first instance systolic hypertension was more in PBSG in all the subgroups except in rural children. Prevalence of diastolic hypertension was significantly higher in PBSG in urban subgroup only. BMI status trends are associated with blood pressure distribution in children.
本研究旨在探讨印度南部某一学校儿童群体中，体重指数（BMI）趋势与当前血压之间的关联。采用分层随机抽样法抽取了 25228 名儿童作为研究对象。2003-2004 年测量了身高和体重。2005-2006 年测量了身高、体重和血压。对共有 12129 名年龄在 5-16 岁、具有配对数据的儿童进行了分析。使用国际儿科参考值将血压和 BMI 值转换为 Z 分数。Z BMI 的增加意味着孩子相对于其年龄和性别，BMI 水平升高。在该队列中，62.4%的儿童在随访时的 Z BMI 高于基线时。Z BMI 较高的儿童被标记为正 BMI 状态组（PBSG），其余为负 BMI 状态组（NBSG）。BMI 的正趋势在农村地区、政府学校和女孩中更为明显。在所有亚组中，PBSG 的收缩压（SBP）均显著高于 NBSG。与 NBSG 相比，PBSG 在城市地区、政府学校和女孩中舒张血压（DBP）显著更高。除农村儿童外，所有亚组中，PBSG 的初发收缩期高血压患病率均较高。仅在城市亚组中，PBSG 的舒张期高血压患病率显著更高。BMI 状态趋势与儿童血压分布有关。
