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城乡青少年持续性高血压和肥胖症的流行情况:印度北部一项基于学校的横断面研究。

Prevalence of sustained hypertension and obesity among urban and rural adolescents: a school-based, cross-sectional study in North India.

机构信息

Cardiology, Hero DMC Heart Institute, Ludhiana, Punjab, India

Cardiology, Hero DMC Heart Institute, Ludhiana, Punjab, India.

出版信息

BMJ Open. 2019 Sep 8;9(9):e027134. doi: 10.1136/bmjopen-2018-027134.

Abstract

OBJECTIVE

Recent data on sustained hypertension and obesity among school-going children and adolescents in India are limited. This study evaluates the prevalence of sustained hypertension and obesity and their risk factors among urban and rural adolescents in northern India.

SETTING

A school-based, cross-sectional survey was conducted in the urban and rural areas of Ludhiana, Punjab, India using standardised measurement tools.

PARTICIPANTS

A total of 1959 participants aged 11-17 years (urban: 849; rural: 1110) were included in this school-based survey.

PRIMARY AND SECONDARY OUTCOME MEASURES

To measure sustained hypertension among school children, two distinct blood pressure (BP) measurements were recorded at an interval of 1 week. High BP was defined and classified into three groups as recommended by international guidelines: (1) normal BP: <90th percentile compared with age, sex and height percentile in each age group; (2) prehypertension: BP=90th-95th percentile; and (3) hypertension: BP >95th percentile. The Indian Academy of Pediatrics classification was used to define underweight, normal, overweight and obesity as per the body mass index (BMI) for specific age groups.

RESULTS

The prevalence of sustained hypertension among rural and urban areas was 5.7% and 8.4%, respectively. The prevalence of obesity in rural and urban school children was 2.7% and 11.0%, respectively. The adjusted multiple regression model found that urban area (relative risk ratio (RRR): 1.7, 95% CI 1.01 to 2.93), hypertension (RRR: 7.4, 95% CI 4.21 to 13.16) and high socioeconomic status (RRR: 38.6, 95% CI 16.54 to 90.22) were significantly associated with an increased risk of obesity. However, self-reported regular physical activity had a protective effect on the risk of obesity among adolescents (RRR: 0.4, 95% CI 0.25 to 0.62). Adolescents who were overweight (RRR: 2.66, 95% CI 1.49 to 4.40) or obese (RRR: 7.21, 95% CI 4.09 to 12.70) and reported added salt intake in their diet (RRR: 4.90, 95% CI 2.83 to 8.48) were at higher risk of hypertension.

CONCLUSION

High prevalence of sustained hypertension and obesity was found among urban school children and adolescents in a northern state in India. Hypertension among adolescents was positively associated with overweight and obesity (high BMI). Prevention and early detection of childhood obesity and high BP should be strengthened to prevent the risk of cardiovascular diseases in adults.

摘要

目的

印度学龄儿童和青少年持续性高血压和肥胖的最新数据有限。本研究评估了印度北部城乡青少年持续性高血压和肥胖的流行情况及其危险因素。

设置

在印度旁遮普邦卢迪亚纳的城乡地区,使用标准化测量工具进行了一项基于学校的横断面调查。

参与者

共有 1959 名 11-17 岁的参与者(城市:849 人;农村:1110 人)纳入了这项基于学校的调查。

主要和次要结果测量

为了测量学龄儿童的持续性高血压,在相隔 1 周的时间内记录了两次不同的血压(BP)测量值。高血压的定义和分类按照国际指南推荐的标准分为三组:(1)正常血压:与每个年龄组的年龄、性别和身高百分位相比,<90 百分位;(2)前期高血压:BP=90-95 百分位;(3)高血压:BP>95 百分位。根据身体质量指数(BMI)为特定年龄组的儿童定义了消瘦、正常、超重和肥胖。

结果

农村和城市地区持续性高血压的患病率分别为 5.7%和 8.4%。农村和城市学龄儿童肥胖的患病率分别为 2.7%和 11.0%。调整后的多因素回归模型发现,城区(相对风险比(RRR):1.7,95%置信区间 1.01 至 2.93)、高血压(RRR:7.4,95%置信区间 4.21 至 13.16)和高社会经济地位(RRR:38.6,95%置信区间 16.54 至 90.22)与肥胖风险增加显著相关。然而,自我报告的定期体育锻炼对青少年肥胖风险有保护作用(RRR:0.4,95%置信区间 0.25 至 0.62)。超重(RRR:2.66,95%置信区间 1.49 至 4.40)或肥胖(RRR:7.21,95%置信区间 4.09 至 12.70)且报告饮食中添加盐的青少年(RRR:4.90,95%置信区间 2.83 至 8.48)患高血压的风险更高。

结论

在印度北部一个邦的城市学龄儿童和青少年中发现了持续性高血压和肥胖的高患病率。青少年高血压与超重和肥胖(高 BMI)呈正相关。应加强儿童肥胖和高血压的预防和早期发现,以预防成年人患心血管疾病的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19ba/6738741/154ab96d0cbd/bmjopen-2018-027134f01.jpg

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